Microstructural tissue changes in Alzheimer disease brains: insights from magnetization transfer imaging

I Colonna, M Koini, L Pirpamer… - American Journal …, 2021 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Reductions in magnetization transfer ratio have been
associated with brain microstructural damage. We aim to compare magnetization transfer …

Regional analysis of the magnetization transfer ratio of the brain in mild Alzheimer disease and amnestic mild cognitive impairment

M Mascalchi, A Ginestroni, V Bessi… - American Journal …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Manually drawn VOI-based analysis shows a decrease in
magnetization transfer ratio in the hippocampus of patients with Alzheimer disease. We …

Magnetization transfer imaging of gray and white matter in mild cognitive impairment and Alzheimer's disease

A Van Es, WM Van der Flier, F Admiraal-Behloul… - Neurobiology of …, 2006 - Elsevier
OBJECTIVE: To assess whether structural brain damage as detected by magnetization
transfer imaging (MTI) in Alzheimer's disease (AD) and mild cognitive impairment (MCI) is …

[HTML][HTML] Magnetization transfer ratio relates to cognitive impairment in normal elderly

S Seiler, L Pirpamer, E Hofer, M Duering… - Frontiers in aging …, 2014 - frontiersin.org
Magnetization transfer imaging (MTI) can detect microstructural brain tissue changes and
may be helpful in determining age-related cerebral damage. We investigated the …

Magnetization transfer ratio in mild cognitive impairment and dementia of Alzheimer's type

NJ Kabani, JG Sled, H Chertkow - Neuroimage, 2002 - Elsevier
Almost half of the elderly subjects that are diagnosed with mild cognitive impairment (MCI)
go on to develop dementia of Alzheimer's type (DAT) over a 5-year follow-up. MCI and DAT …

Quantitative Magnetization Transfer Imaging in Alzheimer Disease1

BH Ridha, DJ Tozer, MR Symms, KC Stockton… - Radiology, 2007 - pubs.rsna.org
Purpose: To prospectively measure magnetization transfer (MT) parameters, along with
established atrophy parameters, in patients with Alzheimer disease (AD) and in age-and sex …

Magnetization transfer ratio in Alzheimer disease: comparison with volumetric measurements

BH Ridha, MR Symms, DJ Tozer… - American journal …, 2007 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Alzheimer disease (AD) is accompanied by macroscopic
atrophy on volumetric MR imaging. A few studies have also demonstrated reduction in …

[HTML][HTML] Pattern of Altered Magnetization Transfer Rate in Alzheimer's Disease

W Duan, P Sehrawat, TD Zhou, JT Becker… - Journal of Alzheimer's …, 2022 - ncbi.nlm.nih.gov
Background: Biomarkers for Alzheimer's disease (AD) are crucial for early diagnosis and
treatment monitoring once disease modifying therapies become available. Objective: This …

Gender, age‐related, and regional differences of the magnetization transfer ratio of the cortical and subcortical brain gray matter

M Mascalchi, N Toschi, A Ginestroni… - Journal of Magnetic …, 2014 - Wiley Online Library
Purpose To explore gender, age‐related, and regional differences of magnetization transfer
ratio (MTR) of brain cortical and subcortical gray matter (GM). Materials and Methods In all …

Longitudinal magnetization transfer imaging in mild to severe Alzheimer disease

S Ropele, R Schmidt, C Enzinger… - American journal …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: MTI has been proposed as a sensitive technique for
studying microstructural brain tissue changes in patients with AD, but the course of these …