BACKGROUND AND PURPOSE: Recent studies showed thalamic atrophy in the early
stages of MS. We investigated the impact of intracortical lesions on the volumes of …

BACKGROUND AND PURPOSE: The role of juxtacortical lesions in brain volume loss in
multiple sclerosis has not been fully clarified. The aim of this study was to explore the role of …

Aims The objective of the study was to assess whether changes in the volume of the
thalamus during the onset of multiple sclerosis predict cognitive impairment after accounting …

Using serial magnetic resonance imaging (MRI), we investigated the relationship between
diffuse cerebral atrophy, T1 and T2 lesion volumes, mean thalamic volumes and clinical …

Purpose To estimate the relative contributions of baseline thalamic atrophy and
abnormalities shown at magnetization transfer (MT) magnetic resonance (MR) imaging, as …

BACKGROUND AND PURPOSE: The association between subcortical deep gray matter,
white matter, and cortical pathology is not well understood in MS. The aim of this study was …

Background: Thalamic pathology is a marker for neurodegeneration and multiple sclerosis
(MS) disease progression. Objective: To characterize (1) the morphology of thalamic …

Objective Thalamic atrophy is among the earliest brain changes detected in patients with
multiple sclerosis (MS) and the degree of thalamic atrophy is a strong predictor of disability …

Objective This study aimed to investigate at 7.0-T MRI a) the role of multiple sclerosis (MS)
cortical lesions in cortical tissue loss b) their relation to neurological disability. Methods In 76 …

Objectives Although whole and individual regional brain volume loss have been separately
reported to correlate with disability in multiple sclerosis (MS), hierarchical cluster analyses of …