We read with interest the recent paper by Barkovich and Peck describing MR features of
Zellweger syndrome (ZS)(1). All six patients in their series had impaired myelination …

PURPOSE To determine characteristic MR imaging features of Zellweger syndrome.
METHODS Clinical records, laboratory records, and MR studies of six patients with …

Case 1 A 6-day-old white infant girl was transferred to Cardinal Glennon Children's Hospital
for evaluation of dysmorphism. She was born to a G2, P2, AbO, mother by spontaneous …

Dear Editor-in-Chief Professor Concezio Di Rocco: Zellweger syndrome (ZS) is the most
severe prototypical member of the peroxisome biogenesis disorders (PBDs), a disease …

Zellweger syndrome (ZS), or cerebrohepatorenal syndrome, was the first described
peroxisomal biogenesis disorder. It represents the most severe phenotype, and some of its …

A term male newborn was noted to have severe diffuse hypotonia, hyporeflexia,
hepatosplenomegaly, and characteristic abnormal facies of Zellweger syndrome, the …

Patients with the cerebrohepatorenal syndrome of Zellweger lack peroxisomes and certain
peroxisomal enzymes such as dihydroxyacetone phosphate acyltransferase in their tissues …

Abstract A 3.5-month-old white male was admitted to hospital to be evaluated for liver
disease. Birth weight was 3,000 g; occipito-frontal head circumference (OFC) was 36-37 cm …

INTRODUCTION: Zellweger syndrome, or cerebrohepatorenal syndrome, is the most
serious form of the peroxisomal diseases. Clinically, it is characterised by the association …

In addition to a distinct malformation (pachymicrogyria, heterotaxic lamination of the
cerebellar cortex, olivary dysplasia), unusual degenerative changes were found in the …