Platelet-function testing in patients undergoing neurovascular procedures: caught between a rock and a hard place

J Comin, DF Kallmes - American Journal of Neuroradiology, 2013 - Am Soc Neuroradiology
In the context of neurointerventional procedures, clopidogrel hyper-responsiveness has
been associated with hemorrhage; on the other hand, clopidogrel resistance has been …

Platelet function testing in neurovascular procedures: tool or gimmick?

NK Cheung, MW Carr, U Ray, D McKenzie… - Interventional …, 2020 - karger.com
Background: Platelet inhibitors are used to prevent thromboembolic complications related to
neurovascular stenting (NVS) procedures. Despite substantial inter-individual variability of …

Dual antiplatelet therapy monitoring for neurointerventional procedures using a point-of-care platelet function test: a single-center experience

DH Lee, A Arat, H Morsi, H Shaltoni… - American journal …, 2008 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Growing evidence of the relationship between poor
antiplatelet response and occurrence of clinical events elicited the need of monitoring the …

[HTML][HTML] Clopidogrel resistance by P2Y12 platelet function testing in patients undergoing neuroendovascular procedures: incidence of ischemic and hemorrhagic …

JD Nordeen, AV Patel, RM Darracott… - Journal of vascular …, 2013 - ncbi.nlm.nih.gov
Purpose: The purpose of the study was to assess clopidogrel resistance and whether
“intensified” antiplatelet therapy guided by platelet inhibition tests during neuroendovascular …

Clopidogrel hyper-response and bleeding risk in neurointerventional procedures

C Goh, L Churilov, P Mitchell… - American Journal of …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Antiplatelet therapy is associated with decreased ischemic
events after neurointerventional procedures. Antiplatelet resistance negates the protective …

Measurement of antiplatelet inhibition during neurointerventional procedures: the effect of antithrombotic duration and loading dose

DJ Pandya, BFM Fitzsimmons, TJ Wolfe… - Journal of …, 2010 - Wiley Online Library
ABSTRACT BACKGROUND/OBJECTIVE Symptomatic thromboembolic events are the most
common complications associated with aneurysm coiling, and carotid and intracranial …

Monitoring of clopidogrel-related platelet inhibition: correlation of nonresponse with clinical outcome in supra-aortic stenting

S Müller-Schunk, J Linn, N Peters… - American Journal …, 2008 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Clopidogrel and aspirin are antiplatelet medications used
in patients intended for endovascular stent placement. Although various studies have …

Accumetrics-based clopidogrel dosing in endovascular neurosurgery

P Wong, E Tesoro, V Aletich, A Alaraj - Neurological research, 2015 - Taylor & Francis
Introduction: The role of the VerifyNow test to guide clopidogrel therapy in neurosurgical
patients is still unclear. This study compared outcomes in patients undergoing …

Clopidogrel resistance in neurovascular stenting: correlations between light transmission aggregometry, VerifyNow, and the Multiplate

N Flechtenmacher, F Kämmerer… - American Journal …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Clopidogrel resistance is blamed for thromboembolic
complications in neurovascular stent placement. Platelet-function assays are weakly …

[HTML][HTML] Variability of platelet reactivity on antiplatelet therapy in neurointervention procedure

HJ Yi, G Hwang, BH Lee - Journal of Korean Neurosurgical Society, 2019 - ncbi.nlm.nih.gov
As more intracranial aneurysms and other cerebrovascular pathologies are treated with
neurointervention procedure, thromboembolic events that frequently lead to serious …