BACKGROUND AND PURPOSE: Lesion load is a common biomarker in multiple sclerosis,
yet it has historically shown modest association with clinical outcome. Lesion count, which …

Background Magnetic resonance imaging (MRI) is used to follow-up multiple sclerosis (MS)
and evaluate disease progression and therapy response via lesion quantification. However …

Purpose Lesion number and burden can predict the long-term outcome of multiple sclerosis,
while the localization of the lesions is also a good predictive marker of disease progression …

PURPOSE To study the utility of a computer-assisted method of quantitating enhancing
multiple sclerosis (MS) lesions and to correlate this quantitation with the type and duration of …

Purpose To explore relations between spatial distribution of multiple sclerosis (MS) lesions,
and disability. In MS, the presence of asymptomatic brain lesions challenges the prediction …

BACKGROUND AND PURPOSE: Detecting incidence and enlargement of lesions is
essential in monitoring the progression of MS. In clinical trials, lesion load is observed by …

BACKGROUND AND PURPOSE The purpose of our study was to investigate the effect of
section thickness on MR detection of brain lesion volume and measurement precision in …

OBJECTIVE The serial quantification of MRI lesion load in multiple sclerosis provides an
effective tool for monitoring disease progression and this has led to its increasing use as an …

Magnetic resonance imaging (MRI) provides a powerful tool for assessing disease activity in
multiple sclerosis (MS), and its role as a surrogate marker for monitoring treatment efficacy is …

OBJECTIVES Quantitative measurement of lesion load on proton density or T2 weighted
brain MRI in multiple sclerosis is a widely used marker of disease progression in treatment …