Correlating quantitative MR imaging with histopathology in X-linked adrenoleukodystrophy

JP van der Voorn, PJW Pouwels… - American journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Quantitative MR imaging techniques may improve the
pathologic specificity of MR imaging regarding white matter abnormalities. Our purposes …

Proton MR spectroscopic and diffusion tensor brain MR imaging in X-linked adrenoleukodystrophy: initial experience

FS Eichler, R Itoh, PB Barker, S Mori, ES Garrett… - Radiology, 2002 - pubs.rsna.org
PURPOSE: To compare conventional magnetic resonance (MR) imaging, proton MR
spectroscopic imaging, and diffusion tensor (DT) MR imaging findings in patients with X …

X-linked adrenoleukodystrophy: the role of contrast-enhanced MR imaging in predicting disease progression

ER Melhem, DJ Loes, CS Georgiades… - American journal …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Early assignment of disease progression among patients
with X-linked adrenoleukodystrophy (ALD) is critical for the appropriate selection of effective …

Magnetic resonance imaging detection of lesion progression in adult patients with X-linked adrenoleukodystrophy

F Eichler, A Mahmood, D Loes, L Bezman… - Archives of …, 2007 - jamanetwork.com
Background An inherited disorder, X-linked adrenoleukodystrophy (X-ALD) is known to
cause progressive inflammatory demyelination. Objective To analyze the adult pattern of …

Seven-Tesla proton magnetic resonance spectroscopic imaging in adult X-linked adrenoleukodystrophy

E Ratai, T Kok, C Wiggins, G Wiggins… - Archives of …, 2008 - jamanetwork.com
Background Adults with X-linked adrenoleukodystrophy (X-ALD) remain at risk for
progressive neurological deterioration. Phenotypes vary in their pathology, ranging from …

Analysis of MRI patterns aids prediction of progression in X-linked adrenoleukodystrophy

DJ Loes, A Fatemi, ER Melhem, N Gupte, L Bezman… - Neurology, 2003 - AAN Enterprises
Background: X-linked adrenoleukodystrophy (X-ALD) has variants with widely different
outcomes, hampering clinical counseling and evaluation of therapies. Objective: To evaluate …

Proton MR spectroscopic imaging predicts lesion progression on MRI in X-linked adrenoleukodystrophy

FS Eichler, PB Barker, C Cox, D Edwin, AM Ulug… - Neurology, 2002 - AAN Enterprises
Background: The phenotypic expression of X-linked adrenoleukodystrophy (X-ALD) ranges
from the rapidly progressive childhood cerebral form to the milder adrenomyeloneuropathy …

The value of new MRI techniques in adrenoleukodystrophy

V Engelbrecht, M Rassek, J Gärtner, T Kahn… - Pediatric …, 1997 - Springer
Purpose. To evaluate the significance of new techniques in MRI examinations of the brain in
children with X-linked adrenoleukodystrophy (ALD). Materials and methods. Five patients …

Improved tissue characterization in adrenoleukodystrophy using magnetization transfer imaging.

ER Melhem, SN Breiter, AM Ulug… - … American journal of …, 1996 - Am Roentgen Ray Soc
We performed this study to evaluate the usefulness of magnetization transfer (MT) imaging
techniques and magnetization transfer ratio (MTR) measurements in assessing patients with …

Diffusion tensor imaging in cases of adrenoleukodystrophy: preliminary experience as a marker for early demyelination?

JFL Schneider, KA Il'yasov… - American journal …, 2003 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Diffusion tensor imaging measures the proton diffusivity
and preferential orientation of the diffusion tensor. X-linked adrenoleukodystrophy is a …