Effects of donepezil on cortical activation in mild cognitive impairment: a pilot double-blind placebo-controlled trial using functional MR imaging
JR Petrella, SE Prince, S Krishnan… - American journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Cholinesterase-inhibitor therapy is approved for treatment
of Alzheimer disease; however, application in patients with mild cognitive impairment (MCI) …
of Alzheimer disease; however, application in patients with mild cognitive impairment (MCI) …
Cortical activation during cholinesterase-inhibitor treatment in Alzheimer disease: preliminary findings from a pharmaco-fMRI study
Objective Cholinesterase inhibitors improve cognitive functioning in Alzheimer disease (AD).
The authors studied, with functional magnetic resonance imaging (fMRI), the neural …
The authors studied, with functional magnetic resonance imaging (fMRI), the neural …
Established donepezil treatment modulates regional brain activation in early Alzheimer's disease
WJ McGeown, MF Shanks… - Current Alzheimer …, 2010 - ingentaconnect.com
Neuroimaging studies of cholinesterase inhibitor (ChEI) treatment in Alzheimer's disease
(AD) have shown the different short and long term actions of ChEIs. fMRI studies of the ChEI …
(AD) have shown the different short and long term actions of ChEIs. fMRI studies of the ChEI …
Cholinergic enhancement of frontal lobe activity in mild cognitive impairment
Cholinesterase inhibitors positively affect cognition in Alzheimer's disease (AD) and other
conditions, but no controlled functional MRI studies have examined where their effects occur …
conditions, but no controlled functional MRI studies have examined where their effects occur …
Donepezil treatment stabilizes functional connectivity during resting state and brain activity during memory encoding in Alzheimer's disease
C Solé-Padullés, D Bartrés-Faz, A Lladó… - Journal of clinical …, 2013 - journals.lww.com
Previous studies with functional magnetic resonance imaging (fMRI) demonstrated a
differential brain activity and connectivity after treatment with donepezil in Alzheimer's …
differential brain activity and connectivity after treatment with donepezil in Alzheimer's …
An MRI substudy of a donepezil clinical trial in mild cognitive impairment
A magnetic resonance imaging (MRI) study was conducted as part of an intervention study
in subjects with amnestic mild cognitive impairment (aMCI) to assess donepezil's treatment …
in subjects with amnestic mild cognitive impairment (aMCI) to assess donepezil's treatment …
Treatment effects of therapeutic cholinesterase inhibitors on visuospatial processing in Alzheimer's disease: a longitudinal functional MRI study
SN Thiyagesh, TFD Farrow, RW Parks… - Dementia and geriatric …, 2010 - karger.com
Abstract Background/Aims: Visuospatial impairments are known to occur in Alzheimer's
disease (AD). We hypothesised that functional magnetic resonance imaging (fMRI) …
disease (AD). We hypothesised that functional magnetic resonance imaging (fMRI) …
Donepezil effects on hippocampal and prefrontal functional connectivity in Alzheimer's disease: preliminary report
L Zaidel, G Allen, CM Cullum… - Journal of …, 2012 - content.iospress.com
We used functional connectivity magnetic resonance imaging (fcMRI) to investigate changes
in interhemispheric brain connectivity in 11 patients with mild Alzheimer's disease (AD) …
in interhemispheric brain connectivity in 11 patients with mild Alzheimer's disease (AD) …
[HTML][HTML] Donepezil effects on cerebral blood flow in older adults with mild cognitive deficits
X Chen, VA Magnotta, K Duff… - The Journal of …, 2006 - Am Neuropsych Assoc
Cerebral blood flow (CBF) was assessed during a verbal recall task using [15O] water
positron emission tomography (PET) in older adults with mild cognitive deficits participating …
positron emission tomography (PET) in older adults with mild cognitive deficits participating …
Donepezil treatment of patients with MCI: a 48-week randomized, placebo-controlled trial
RS Doody, SH Ferris, S Salloway, Y Sun, R Goldman… - Neurology, 2009 - AAN Enterprises
Background: Treatment of mild cognitive impairment (MCI) with cholinesterase inhibitors
may improve symptoms. Methods: In this multicenter, randomized, placebo-controlled trial …
may improve symptoms. Methods: In this multicenter, randomized, placebo-controlled trial …
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