MR imaging–based analysis of glioblastoma multiforme: estimation of IDH1 mutation status

K Yamashita, A Hiwatashi, O Togao… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Glioblastoma multiforme is highly aggressive and the most
common type of primary malignant brain tumor in adults. Imaging biomarkers may provide …

Less invasive phenotype found in isocitrate dehydrogenase–mutated glioblastomas than in isocitrate dehydrogenase wild-type glioblastomas: a diffusion-tensor …

SJ Price, K Allinson, H Liu, NR Boonzaier, JL Yan… - Radiology, 2017 - pubs.rsna.org
Purpose To explore the diffusion-tensor (DT) imaging–defined invasive phenotypes of both
isocitrate dehydrogenase (IDH-1)–mutated and IDH-1 wild-type glioblastomas. Materials …

Reliability of noncontrast-enhancing tumor as a biomarker of IDH1 mutation status in glioblastoma

A Lasocki, A Tsui, F Gaillard, M Tacey… - Journal of Clinical …, 2017 - Elsevier
Abstract Isocitrate dehydrogenase 1 (IDH1) mutations in gliomas have been associated with
a frontal lobe location and a greater proportion of noncontrast-enhancing tumour (nCET) …

Increased sensitivity to radiochemotherapy in IDH1 mutant glioblastoma as demonstrated by serial quantitative MR volumetry

AN Tran, A Lai, S Li, WB Pope, S Teixeira… - Neuro …, 2014 - academic.oup.com
Abstract Background Isocitrate dehydrogenase 1 (IDH1) mutations have been linked to
favorable outcomes in patients with glioblastoma multiforme (GBM). Recent in vitro …

Invasion and proliferation kinetics in enhancing gliomas predict IDH1 mutation status

AL Baldock, K Yagle, DE Born, S Ahn… - Neuro …, 2014 - academic.oup.com
Background Glioblastomas with a specific mutation in the isocitrate dehydrogenase 1 (IDH1)
gene have a better prognosis than gliomas with wild-type IDH1. Methods Here we compare …

Evaluation of the microenvironmental heterogeneity in high-grade gliomas with IDH1/2 gene mutation using histogram analysis of diffusion-weighted imaging and …

S Lee, SH Choi, I Ryoo, TJ Yoon, TM Kim… - Journal of neuro …, 2015 - Springer
The purpose of our study was to explore the difference between isocitrate dehydrogenase
(IDH)-1/2 gene mutation-positive and-negative high-grade gliomas (HGGs) using histogram …

Radiological features combined with IDH1 status for predicting the survival outcome of glioblastoma patients

K Wang, Y Wang, X Fan, J Wang, G Li, J Ma… - Neuro …, 2015 - academic.oup.com
Background Radiological characteristics may reflect the biological features of brain tumors
and may be associated with genetic alterations that occur in tumorigenesis. This study …

Whole-tumor histogram and texture analyses of DTI for evaluation of IDH1-mutation and 1p/19q-codeletion status in World Health Organization grade II gliomas

YW Park, K Han, SS Ahn, YS Choi… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Prediction of the isocitrate dehydrogenase 1 (IDH1)-
mutation and 1p/19q-codeletion status of World Health Organization grade ll gliomas …

Prediction of IDH1 mutation status in glioblastoma using machine learning technique based on quantitative radiomic data

MH Lee, J Kim, ST Kim, HM Shin, HJ You, JW Choi… - World neurosurgery, 2019 - Elsevier
Objective Isocitrate dehydrogenase 1 (IDH1) mutation status is an independent favorable
prognostic factor for glioblastoma (GBM) and is usually determined by sequencing or …

Patterns of tumor contrast enhancement predict the prognosis of anaplastic gliomas with IDH1 mutation

YY Wang, K Wang, SW Li, JF Wang… - American Journal …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: It is proposed that isocitrate dehydrogenase 1 (IDH1)
mutation predicts the outcome in patients with high-grade glioma. In addition, contrast …