Functional and structural connectivity patterns associated with clinical outcomes in deep brain stimulation of the globus pallidus internus for generalized dystonia

L Okromelidze, T Tsuboi, RS Eisinger… - American Journal …, 2020 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Deep brain stimulation is a well-established treatment for
generalized dystonia, but outcomes remain variable. Establishment of an imaging marker to …

Defining a therapeutic target for pallidal deep brain stimulation for dystonia

T Cheung, AM Noecker, RL Alterman… - Annals of …, 2014 - Wiley Online Library
Objective To create a data‐driven computational model that identifies brain regions most
frequently influenced by successful deep brain stimulation (DBS) of the globus pallidus (GP) …

Mapping efficacious deep brain stimulation for pediatric dystonia

A Coblentz, GJB Elias, A Boutet, J Germann… - Journal of …, 2021 - thejns.org
OBJECTIVE The objective of this study was to report the authors' experience with deep brain
stimulation (DBS) of the internal globus pallidus (GPi) as a treatment for pediatric dystonia …

Intermuscular coherence as biomarker for pallidal deep brain stimulation efficacy in dystonia

E Doldersum, JC Van Zijl, M Beudel, H Eggink… - Clinical …, 2019 - Elsevier
Objective Finding a non-invasive biomarker for Globus Pallidus interna Deep Brain
Stimulation (GPi-DBS) efficacy. Dystonia heterogeneity leads to a wide variety of clinical …

Microelectrode-guided implantation of deep brain stimulators into the globus pallidus internus for dystonia: techniques, electrode locations, and outcomes

PA Starr, RS Turner, G Rau, N Lindsey, S Heath… - Neurosurgical …, 2004 - thejns.org
Object Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a promising new
procedure for the treatment of dystonia. The authors present their technical approach for …

Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia

A Horn, MM Reich, S Ewert, N Li… - Proceedings of the …, 2022 - National Acad Sciences
Dystonia is a debilitating disease with few treatment options. One effective option is deep
brain stimulation (DBS) to the internal pallidum. While cervical and generalized forms of …

[HTML][HTML] Bilateral deep-brain stimulation of the globus pallidus in primary generalized dystonia

M Vidailhet, L Vercueil, JL Houeto… - … England Journal of …, 2005 - Mass Medical Soc
Background Severe forms of dystonia respond poorly to medical treatment. Deep-brain
stimulation is a reversible neurosurgical procedure that has been used for the treatment of …

Cortical network fingerprints predict deep brain stimulation outcome in dystonia

G Gonzalez‐Escamilla, M Muthuraman… - Movement …, 2019 - Wiley Online Library
Background Deep brain stimulation (DBS) is an effective evidence‐based therapy for
dystonia. However, no unequivocal predictors of therapy responses exist. We investigated …

[HTML][HTML] Pallidal deep-brain stimulation in primary generalized or segmental dystonia

A Kupsch, R Benecke, J Müller… - … England Journal of …, 2006 - Mass Medical Soc
Background Neurostimulation of the internal globus pallidus has been shown to be effective
in reducing symptoms of primary dystonia. We compared this surgical treatment with sham …

Meta-regression analysis of the long-term effects of pallidal and subthalamic deep brain stimulation for the treatment of isolated dystonia

YS Wu, LH Ni, RM Fan, MY Yao - World neurosurgery, 2019 - Elsevier
Objective The globus pallidus internus (GPi) and subthalamic nucleus (STN) are therapeutic
targets for deep brain stimulation (DBS) in the treatment of isolated dystonia. We conducted …