Discussion Alexander disease is a progressive neurodegenerative disorder with three
clinical subgroups. The infantile group is characterized by early onset of megalencephaly …

The clinical, radiologic, neurophysiologic, and pathologic findings in 10 children with
histologically proven Alexander's disease are described, and the presence of two broad …

A 10-month-old boy with Alexander disease is described. He was clinically characterized by
early onset of megalencephaly, psychomotor retardation, spasticity and recurrent seizure …

Alexander's disease is reported in a 6-month-old infant. The clinical course was
characterized by hydrocephalus, irritability and psychomotor retardation, with subsequent …

PREVIOUS descriptions of Alexander's disease have generally been of cases in young
children. 1-8 The clinical picture most often associated with this disease has been one of …

We describe 2 new cases of Alexander's disease, the first to be reported in Belgium. The first
patient, a 4‐year‐old girl, presented with progressive megalencephaly, mental retardation …

We report the case of a 40-year-old woman with Alexander disease. She experienced single
seizure as 1-year-old, and became less active after that. Her academic records in …

Alexander's disease, a rare and fatal disorder of the central nervous system, most commonly
affects infants and young children but can also occur in older children and sometimes adults …

A 17-year-old male was diagnosed as having Alexander disease from the clinical
manifestations (psychomotor deterioration and megalencephaly), neuroradiologic findings …

Alexander disease is a rare neurodegenerative disorder. Its most frequent subtype, the
infantile form, is characterized by an early onset and a rapid neurological deterioration …