Patterns of brain structural changes in first-contact, antipsychotic drug-naive patients with schizophrenia

M Filippi, E Canu, R Gasparotti… - American Journal …, 2014 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Previous studies have suggested that structural changes
do occur in the brain of patients with schizophrenia compared with healthy control …

Brain structural changes associated with chronicity and antipsychotic treatment in schizophrenia

L Tomelleri, J Jogia, C Perlini, M Bellani, A Ferro… - European …, 2009 - Elsevier
Accumulating evidence suggest a life-long impact of disease related mechanisms on brain
structure in schizophrenia which may be modified by antipsychotic treatment. The aim of the …

Gray matter volume changes following antipsychotic therapy in first-episode schizophrenia patients: a longitudinal voxel-based morphometric study

F Guo, YQ Zhu, C Li, XR Wang, HN Wang… - Journal of psychiatric …, 2019 - Elsevier
Despite evidence of structural brain abnormalities in schizophrenia, the current study aimed
to explore the effects of antipsychotic treatment on gray matter (GM) volume using structural …

[HTML][HTML] Structural brain changes associated with antipsychotic treatment in schizophrenia as revealed by voxel-based morphometric MRI: an activation likelihood …

US Torres, E Portela-Oliveira, S Borgwardt, GF Busatto - BMC psychiatry, 2013 - Springer
Background The results of multiple studies on the association between antipsychotic use
and structural brain changes in schizophrenia have been assessed only in qualitative …

Brain morphology in antipsychotic-naive schizophrenia: a study of multiple brain structures

W Cahn, HEH Pol, M Bongers, HG Schnack… - The British Journal of …, 2002 - cambridge.org
BackgroundAlthough brain volume changes are found in schizophrenia, only a limited
number of structural magnetic resonance imaging studies have exclusively examined …

[HTML][HTML] Regional abnormality of grey matter in schizophrenia: effect from the illness or treatment?

Y Yue, L Kong, J Wang, C Li, L Tan, H Su, Y Xu - PLoS One, 2016 - journals.plos.org
Both schizophrenia and antipsychotic treatment are known to modulate brain morphology.
However, it is difficult to establish whether observed structural brain abnormalities are due to …

Morphological profiling of schizophrenia: cluster analysis of MRI-based cortical thickness data

Y Pan, W Pu, X Chen, X Huang, Y Cai… - Schizophrenia …, 2020 - academic.oup.com
The diagnosis of schizophrenia is thought to embrace several distinct subgroups. The
manifold entities in a single clinical patient group increase the variance of biological …

Association between structural and functional brain alterations in drug-free patients with schizophrenia: a multimodal meta-analysis

X Gao, W Zhang, L Yao, Y Xiao, L Liu, J Liu, S Li… - Journal of Psychiatry and …, 2018 - jpn.ca
Background: Neuroimaging studies have shown both structural and functional abnormalities
in patients with schizophrenia. Recently, studies have begun to explore the association …

Longitudinal volumetric MRI study in first-and multiple-episode male schizophrenia patients

AB Whitworth, G Kemmler, M Honeder… - Psychiatry Research …, 2005 - Elsevier
In this longitudinal study we compared brain volume changes in first-and multiple-episode
patients with schizophrenia to normal aging changes observed in healthy control subjects …

Anatomical and functional brain abnormalities in drug-naive first-episode schizophrenia

W Ren, S Lui, W Deng, F Li, M Li… - American Journal of …, 2013 - Am Psychiatric Assoc
Objective The authors sought to explore whether anatomical and functional brain deficits are
present in similar or different brain regions early in the course of schizophrenia, before …