BACKGROUND AND PURPOSE: Manually drawn VOI-based analysis shows a decrease in
magnetization transfer ratio in the hippocampus of patients with Alzheimer disease. We …

BACKGROUND AND PURPOSE: Reductions in magnetization transfer ratio have been
associated with brain microstructural damage. We aim to compare magnetization transfer …

Almost half of the elderly subjects that are diagnosed with mild cognitive impairment (MCI)
go on to develop dementia of Alzheimer's type (DAT) over a 5-year follow-up. MCI and DAT …

Purpose: To prospectively measure magnetization transfer (MT) parameters, along with
established atrophy parameters, in patients with Alzheimer disease (AD) and in age-and sex …

We measured magnetization transfer ratios (MTRs) of the hippocampus in 38 patients with
Alzheimer's disease (AD), including very mild (Clinical Dementia Rating [CDR] 0.5, n= 12) …

BACKGROUND AND PURPOSE: Alzheimer disease (AD) is accompanied by macroscopic
atrophy on volumetric MR imaging. A few studies have also demonstrated reduction in …

OBJECTIVE: To assess whether structural brain damage as detected by magnetization
transfer imaging (MTI) in Alzheimer's disease (AD) and mild cognitive impairment (MCI) is …

BACKGROUND AND PURPOSE: Although atrophy of structures in the medial temporal lobe
has been considered an indication of Alzheimer's disease (AD), atrophic changes on MR …

Background: Biomarkers for Alzheimer's disease (AD) are crucial for early diagnosis and
treatment monitoring once disease modifying therapies become available. Objective: This …

The purpose of this study was to assess whether structural brain damage as detected by
volumetric magnetization transfer imaging (MTI) is present in mild cognitive impairment …