Proton MR spectroscopy in the evaluation of cerebral metabolism in patients with fibromyalgia: comparison with healthy controls and correlation with symptom severity

M Petrou, RE Harris, BR Foerster… - American journal …, 2008 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Widespread pain sensitivity in patients with fibromyalgia
(FM) suggests a central nervous system (CNS)-processing problem. Therefore, it is …

Metabolic abnormalities in pain-processing regions of patients with fibromyalgia: a 3T MR spectroscopy study

P Feraco, A Bacci, F Pedrabissi… - American journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: A growing body of evidence suggests the involvement of
the brain in FM. The purpose of this proton MRS study was to test the hypothesis that there …

Brain dysfunction in fibromyalgia and somatization disorder using proton magnetic resonance spectroscopy: a controlled study

N Fayed, E Andres, G Rojas, S Moreno… - Acta Psychiatrica …, 2012 - Wiley Online Library
Fayed N, Andres E, Rojas G, Moreno S, Serrano‐Blanco A, Roca M, Garcia‐Campayo J.
Brain dysfunction in fibromyalgia and somatization disorder using proton magnetic …

[HTML][HTML] Hippocampal metabolite abnormalities in fibromyalgia: correlation with clinical features

PB Wood, CR Ledbetter, MF Glabus, LK Broadwell… - The Journal of …, 2009 - Elsevier
Although the pathology of fibromyalgia is poorly understood, a growing body of evidence
suggests involvement of the central nervous system. The hippocampus is a brain center that …

Cerebral blood flow alterations in pain-processing regions of patients with fibromyalgia using perfusion MR imaging

BR Foerster, M Petrou, RE Harris… - American Journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Widespread pain sensitivity in patients with FM suggests a
CNS processing problem. The purpose of this study was to assess alterations in perfusion …

Hippocampus dysfunction may explain symptoms of fibromyalgia syndrome. A study with single-voxel magnetic resonance spectroscopy

Y Emad, Y Ragab, F Zeinhom, G El-Khouly… - The Journal of …, 2008 - jrheum.org
Objective (1) To investigate dysfunction of hippocampus in patients with fibromyalgia
syndrome (FM) using proton magnetic resonance spectroscopy (1H-MRS), and to compare …

Increased glutamate/glutamine compounds in the brains of patients with fibromyalgia: a magnetic resonance spectroscopy study

M Valdés, A Collado, N Bargalló… - Arthritis & …, 2010 - Wiley Online Library
Objective Fibromyalgia (FM) has been defined as a systemic disorder that is clinically
characterized by pain, cognitive deficit, and the presence of associated psychopathology, all …

Neuroimaging of fibromyalgia

RH Gracely, KR Ambrose - Best practice & research Clinical rheumatology, 2011 - Elsevier
The primary symptom of fibromyalgia is widespread pain. This symptom is accompanied by
secondary symptoms, such as cognitive difficulties and sensitivity to painful stimulation, and …

[HTML][HTML] Gray matter volumes of pain-related brain areas are decreased in fibromyalgia syndrome

ME Robinson, JG Craggs, DD Price, WM Perlstein… - The journal of pain, 2011 - Elsevier
Fibromyalgia (FM) is a chronic, widespread musculoskeletal pain disorder that is very
prevalent in the general population (approximately 5%). Accumulating evidence suggests …

Neurochemical correlates of brain atrophy in fibromyalgia syndrome: A magnetic resonance spectroscopy and cortical thickness study

P Feraco, S Nigro, L Passamonti, A Grecucci… - Brain Sciences, 2020 - mdpi.com
(1) Background: Recently, a series of clinical neuroimaging studies on fibromyalgia (FM)
have shown a reduction in cortical volume and abnormally high glutamate (Glu) and …