BACKGROUND AND PURPOSE: DTI can provide in vivo information about the pathology of
optic nerve disease, but there is no study of DTI in the setting of ION, the most frequent acute …

Objective To evaluate directional diffusivities within the optic nerve in a first event of acute
optic neuritis to determine whether decreased axial diffusivity (AD) would predict 6-month …

Objectives To assess the impact of timing from visual symptoms' onset to diffusion-weighted
(DW) 3 T MRI completion to detect ischemic changes of the optic disc and optic nerve in …

Previous studies have reported diffusion tensor imaging (DTI) changes within the optic
radiations of patients after optic neuritis (ON). We aimed to study optic radiation DTI changes …

Ischemic optic neuropathies (IONs) are among the most prevalent diseases causing visual
impairment in middle-aged and elderly people. While arteritic ION is an ocular emergency …

BACKGROUND AND PURPOSE: Increases in apparent diffusion coefficient (ADC) from
diffusion-weighted (DW) imaging are thought to be due to axonal disruption, and changes …

Background Early markers of axonal and clinical outcomes are required for early phase
testing of putative neuroprotective therapies for multiple sclerosis (MS). Objectives To …

BACKGROUND AND PURPOSE: Abnormal signal intensity of the optic nerve due to
diffusion restriction may be seen in traumatic optic neuropathy. In addition to evaluating optic …

Purpose Diffusion magnetic resonance imaging (MRI) is commonly used in acute stroke, but
not considered diagnostic in ischemic optic neuropathy. This study evaluates the presence …

Background Indirect traumatic optic neuropathy (ITON) is a devastating cause of permanent
visual loss. Axonal degeneration, the characteristic pathological change of ITON, cannot be …