BACKGROUND AND PURPOSE: In multiple sclerosis (MS), autologous hematopoietic stem
cell transplantation (AHSCT) induces a profound suppression of clinical activity and MR …

Using MRI, we measured disease activity and brain atrophy in nine multiple sclerosis
patients treated with autologous hematopoietic stem cell transplantation (AHSCT) for a …

Background: A cohort of patients with poor-prognosis multiple sclerosis (MS) underwent
chemotherapy-based immune ablation followed by immune reconstitution with an …

To assess whether brain tissue loss occurs after profound and sustained suppression of
magnetic resonance imaging (MRI) enhancement, we measured brain volume changes from …

Background Individuals with MS undergoing immunoablative therapy and hematopoietic
stem cell transplantation (HSCT) show substantial decrease in brain volume over 2.4 …

Background: Autologous haematopoietic stem cell transplantation (aHSCT) is a valuable
option in aggressive relapsing–remitting multiple sclerosis (MS), but its efficacy in secondary …

Objectives To determine whether treatment with autologous hematopoietic stem cell
transplantation (HSCT) can induce sustained complete remission in patients with multiple …

Combined assessment of latest-generation molecular and MRI biomarkers has provided
insight into the dynamics of brain volume loss after immunoablative autologous …

Background: Immunoablation and autologous hematopoietic stem cell transplantation
(IA/aHSCT) halts relapses, white matter (WM) lesion formation, and pathological whole-brain …

The purpose of the study was to determine the long-term safety and effectiveness of high-
dose immunosuppressive therapy (HDIT) followed by autologous hematopoietic cell …