BACKGROUND AND PURPOSE: Research on the association between Propionibacterium
acnes in the disc space and type 1 Modic changes in adjacent vertebrae is limited and has …

Background: Recent studies suggest an association between sciatica and
Propionibacterium acnes.“Modic type I changes” in the vertebrae are closely associated with …

This review presents a summary of the pathology and epidemiology of Modic changes and
the possible role of Propionibacterium acnes. This information is followed by a synthesis of …

Modic type I change (MC1) are vertebral bone marrow lesions adjacent to degenerated
discs that are specific for discogenic low back pain. The etiopathogenesis is unknown, but …

Abstract Introduction Modic changes (MCs) in vertebral bones are induced by two
mechanisms of mechanical factors and infection. As Propionibacterium acnes (P. acnes) …

Background: Modic changes (inflammatory-like changes visible on magnetic resonance
imaging [MRI] scans of a vertebral end plate) are common and are associated with low back …

Abstract Purpose Intervertebral disc with Propionibacterium acnes (P. acnes) is suggested to
be an etiology of Modic type I changes in the adjacent bone marrow. However it is unknown …

Study Design. A case-control study of animal model of Modic changes (MCs) on rabbits.
Objective. To evaluate the feasibility of inducing of MCs by injection of Propionibacterium …

Introduction Multiple reports of bacterial isolates in human disc tissue have suggested a role
of low-grade infection on intervertebral disc degeneration and modic changes (MC) …

Study design A prospective cross-sectional case series study. Objective To investigate the
prevalence of low virulence disc infection and its associations with characteristics of patients …