BACKGROUND AND PURPOSE: Survivors of acute lymphoblastic leukemia are at risk for
neurocognitive deficits and leukoencephalopathy. We performed a longitudinal assessment …

Background Leukoencephalopathy is observed in some children undergoing chemotherapy
for acute lymphoblastic leukaemia, although its effects on long-term outcomes is unknown …

PURPOSE: Intravenous methotrexate (IV-MTX), an effective treatment for acute
lymphoblastic leukemia (ALL), has a significant toxic effect on the central nervous system …

Objectives The most common form of pediatric cancer is acute lymphoblastic leukemia
(ALL). Magnetic resonance (MR) neuroimaging studies have revealed leukoencephalopathy …

Purpose To look for the presence and age‐dependence of late structural alterations of
otherwise normal‐appearing cerebral gray and white matter after radiation and …

Survivors of childhood acute lymphoblastic leukaemia are at risk for neurocognitive
impairment, though little information is available on its association with brain integrity …

Background The effect of chemotherapy on brain development in long-term survivors of
pediatric acute lymphoblastic leukemia (ALL) was systematically reviewed. Methods A …

BACKGROUND The objective of this study was to evaluate changes in magnetic resonance
imaging (MRI) of the brain in children with acute lymphoblastic leukemia (ALL) during the …

Abstract Background and Methods. Twenty‐seven children with acute lymphoblastic
leukemia (ALL) were studied by magnetic resonance (MR) imaging after central nervous …

Acute lymphoblastic leukaemia (ALL) is the most common malignancy in children. Although
the survival rate has increased dramatically over the last decades, patients struggle with the …