BACKGROUND AND PURPOSE: Among the several reports of elastase-induced aneurysm
models, only the rabbit common carotid artery (CCA) model has been used for testing …

BACKGROUND AND PURPOSE: Elastase-induced aneurysms in rabbits have become an
accepted model to study endovascular treatment. The size and shape of the resulting …

BACKGROUND AND PURPOSE: Long-term patency in untreated experimental aneurysms
represents a critical attribute of any system proposed for the testing of aneurysm occlusion …

BACKGROUND AND PURPOSE: There is no report regarding patency of elastase-induced
aneurysms for more than a 2-year period. Our aim was to report aneurysm patency rates up …

Preclinical studies are important in helping practitioners and device developers improve
techniques and tools for endovascular treatment of intracranial aneurysms. Thus an …

BACKGROUND AND PURPOSE: Animal models with appropriate volume are crucial for
preclinical assessment of aneurysm therapies. Our purpose was to control the aneurysm …

BACKGROUND AND PURPOSE: The development of more effective intracranial aneurysm
therapy depends on the ability to test various intravascular occlusion devices and …

BACKGROUND AND PURPOSE: Reproducible animal models facilitate preclinical
assessment of aneurysm therapies. Our purpose was to determine if increased elastase …

Introduction The purpose of this study was to create morphologically reproducible elastase-
induced model aneurysms in rabbits. Methods We created 120 elastase-induced aneurysms …

OBJECTIVE: To develop a new saccular aneurysm model in vitro using elastase to study
aneurysm initiation, growth, and rupture and to create a new in vivo aneurysm model to test …