BACKGROUND AND PURPOSE: Induced hypothermia is thought to work partly by
mitigating reperfusion injury in asphyxiated term neonates. The purpose of this study was to …

BACKGROUND AND PURPOSE: Cerebral perfusion patterns in neonates with HIE after
therapeutic hypothermia have not been well described. The objectives of this study were to …

Many asphyxiated newborns still develop brain injury despite hypothermia therapy. The
development of brain injury in these newborns has been related partly to brain perfusion …

Objective To assess whether the brain MRI results obtained during hypothermia identify the
later brain injury observed in asphyxiated newborns after therapy is completed. Patients and …

Objective The purposes of this feasibility study were to assess:(1) the potential utility of early
brain MRI in asphyxiated newborns treated with hypothermia;(2) whether early MRI predicts …

OBJECTIVE: To compare the association between perinatal events and the pattern and
extent of brain injury on early magnetic resonance imaging in newborn infants with and …

Background: Perinatal asphyxia remains one of the most devastating neurologic processes.
There is experimental and clinical evidence that cerebral cooling may suppress the …

Background Therapeutic hypothermia is the standard-of-care treatment for infants
diagnosed with moderate-to-severe hypoxic–ischemic encephalopathy (HIE). MRI for …

Objective To evaluate the electrographic seizure burden in neonates with hypoxic ischemic
encephalopathy (HIE) treated with or without therapeutic hypothermia and stratified results …

Background Moderate hypothermia in neonates with hypoxic–ischaemic encephalopathy
might improve survival and neurological outcomes at up to 18 months of age, although …