A multiparametric model for mapping cellularity in glioblastoma using radiographically localized biopsies

PD Chang, HR Malone, SG Bowden… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The complex MR imaging appearance of glioblastoma is a
function of underlying histopathologic heterogeneity. A better understanding of these …

Regional variation in histopathologic features of tumor specimens from treatment-naive glioblastoma correlates with anatomic and physiologic MR Imaging

RF Barajas Jr, JJ Phillips, R Parvataneni… - Neuro …, 2012 - academic.oup.com
Histopathologic evaluation of glioblastoma multiforme (GBM) at initial diagnosis is typically
performed on tissue obtained from regions of contrast enhancement (CE) as depicted on …

Multimodal MR imaging model to predict tumor infiltration in patients with gliomas

CR Durst, P Raghavan, ME Shaffrey, D Schiff… - Neuroradiology, 2014 - Springer
Introduction Gliomas remain difficult to treat, in part, due to our inability to accurately
delineate the margins of the tumor. The goal of our study was to evaluate if a combination of …

Tumor infiltration in enhancing and non-enhancing parts of glioblastoma: a correlation with histopathology

O Eidel, S Burth, JO Neumann, PJ Kieslich, F Sahm… - PloS one, 2017 - journals.plos.org
Purpose To correlate histopathologic findings from biopsy specimens with their
corresponding location within enhancing areas, non-enhancing areas and necrotic areas on …

Morphological and flow cytometric analysis of cell infiltration in glioblastoma: a comparison of autopsy brain and neuroimaging

T Yamahara, Y Numa, T Oishi, T Kawaguchi… - Brain tumor …, 2010 - Springer
Even when we successfully perform a total extirpation of glioblastoma macroscopically, we
often encounter tumor recurrence. We examined seven autopsy brains, focusing on tumor …

Radio-pathomic maps of cell density identify brain tumor invasion beyond traditional MRI-defined margins

SA Bobholz, AK Lowman, M Brehler… - American Journal …, 2022 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Currently, contrast-enhancing margins on T1WI are used
to guide treatment of gliomas, yet tumor invasion beyond the contrast-enhancing region is a …

Non-invasive assessment of glioma microstructure using VERDICT MRI: correlation with histology

F Zaccagna, F Riemer, AN Priest, MA McLean… - European …, 2019 - Springer
Purpose This prospective study evaluated the use of vascular, extracellular and restricted
diffusion for cytometry in tumours (VERDICT) MRI to investigate the tissue microstructure in …

[HTML][HTML] Tissue-type mapping of gliomas

F Raschke, TR Barrick, TL Jones, G Yang, X Ye… - NeuroImage: Clinical, 2019 - Elsevier
Purpose To develop a statistical method of combining multimodal MRI (mMRI) of adult glial
brain tumours to generate tissue heterogeneity maps that indicate tumour grade and …

Glioblastoma multiforme regional genetic and cellular expression patterns: influence on anatomic and physiologic MR imaging

RF Barajas Jr, JG Hodgson, JS Chang… - Radiology, 2010 - pubs.rsna.org
Purpose To determine whether magnetic resonance (MR) imaging is influenced by genetic
and cellular features of glioblastoma multiforme (GBM) aggressiveness. Materials and …

Super-resolution track density imaging of glioblastoma: histopathologic correlation

RF Barajas, CP Hess, JJ Phillips… - American Journal …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Super-resolution track density imaging generates
anatomic images with submillimeter voxel resolution by using high-angular-resolution …