Proton resonance frequency chemical shift thermometry: experimental design and validation toward high-resolution noninvasive temperature monitoring and in vivo …

S Dehkharghani, H Mao, L Howell… - American Journal …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Applications for noninvasive biologic temperature
monitoring are widespread in biomedicine and of particular interest in the context of brain …

MR thermometry in cerebrovascular disease: physiologic basis, hemodynamic dependence, and a new frontier in stroke imaging

S Dehkharghani, D Qiu - American Journal of …, 2020 - Am Soc Neuroradiology
The remarkable temperature sensitivity of the brain is widely recognized and has been
studied for its role in the potentiation of ischemic and other neurologic injuries. Pyrexia …

Measurement of regional brain temperature using proton spectroscopic imaging: validation and application to acute ischemic stroke

I Marshall, B Karaszewski, JM Wardlaw, V Cvoro… - Magnetic resonance …, 2006 - Elsevier
A magnetic resonance proton spectroscopic imaging (SI) technique was developed to
measure regional brain temperatures in human subjects. The technique was validated in a …

Cerebral temperature dysregulation: MR thermographic monitoring in a nonhuman primate study of acute ischemic stroke

S Dehkharghani, CC Fleischer, D Qiu… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Cerebral thermoregulation remains poorly understood.
Temperature dysregulation is deeply implicated in the potentiation of cerebrovascular …

Magnetic resonance spectroscopy thermometry at 3 tesla: importance of calibration measurements

M Verius, F Frank, E Gizewski… - Therapeutic Hypothermia …, 2019 - liebertpub.com
To demonstrate the importance of calibration measurements in 3 Tesla proton magnetic
resonance (MR) spectroscopy (1H-MRS) thermometry for human brain temperature …

Noninvasive measurements of human brain temperature using volume-localized proton magnetic resonance spectroscopy

R Corbett, A Laptook… - Journal of Cerebral Blood …, 1997 - journals.sagepub.com
Elucidation of the role of cerebral hyperthermia as a secondary factor that worsens outcome
after brain injury, and the therapeutic application of modest brain hypothermia would benefit …

Improving the reproducibility of proton magnetic resonance spectroscopy brain thermometry: Theoretical and empirical approaches

Z Dong, JT Kantrowitz, JJ Mann - NMR in Biomedicine, 2022 - Wiley Online Library
In proton magnetic resonance spectroscopy (1H MRS)‐based thermometry of brain,
averaging temperatures measured from more than one reference peak offers several …

Measurement of brain temperature with magnetic resonance spectroscopy in acute ischemic stroke

B Karaszewski, JM Wardlaw, I Marshall… - Annals of …, 2006 - Wiley Online Library
Objective Pyrexia is associated with poor outcome after stroke, but the temperature changes
in the brain after stroke are poorly understood. We used magnetic resonance spectroscopic …

Improved calibration technique for in vivo proton MRS thermometry for brain temperature measurement

M Zhu, A Bashir, JJ Ackerman… - Magnetic resonance in …, 2008 - Wiley Online Library
The most common MR‐based approach to noninvasively measure brain temperature relies
on the linear relationship between the 1H MR resonance frequency of tissue water and the …

The brain thermal response as a potential neuroimaging biomarker of cerebrovascular impairment

CC Fleischer, J Wu, D Qiu, SE Park… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Brain temperature is critical for homeostasis, relating
intimately to cerebral perfusion and metabolism. Cerebral thermometry is historically …