Diffusion tensor–MRI evidence for extra-axonal neuronal degeneration in caudate and thalamic nuclei of patients with multiple sclerosis

S Hannoun, F Durand-Dubief… - American Journal …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: MS is an inflammatory demyelinating disease affecting
both WM and GM. While WM lesions are easily visualized by conventional MR imaging, the …

[HTML][HTML] Gray matter atrophy is primarily related to demyelination of lesions in multiple sclerosis: a diffusion tensor imaging MRI study

E Tóth, N Szabó, G Csete, A Király, P Faragó… - Frontiers in …, 2017 - frontiersin.org
Objective: Cortical pathology, periventricular demyelination, and lesion formation in multiple
sclerosis (MS) are related (Hypothesis 1). Factors in the cerebrospinal fluid close to these …

Quantification of brain gray matter damage in different MS phenotypes by use of diffusion tensor MR imaging

M Bozzali, M Cercignani, MP Sormani… - American Journal …, 2002 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Increasing evidence exists that cerebral gray matter (GM)
from patients with multiple sclerosis (MS) is not spared. This study was performed to quantify …

Microstructural magnetic resonance imaging of cortical lesions in multiple sclerosis

M Filippi, P Preziosa, E Pagani… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: Pathologic and magnetic resonance imaging (MRI) studies have shown that
cortical lesions (CLs) are a frequent finding in multiple sclerosis (MS). Objective: To quantify …

Caudate nuclei volume, diffusion tensor metrics, and T2 relaxation in healthy adults and relapsing‐remitting multiple sclerosis patients: Implications for understanding …

KM Hasan, C Halphen, A Kamali… - Journal of Magnetic …, 2009 - Wiley Online Library
Purpose To investigate the utility of caudate nuclei (CN) macro‐and microstructural metrics
as markers of gray matter degeneration in healthy adults and relapsing‐remitting multiple …

Cortical diffusion-tensor imaging abnormalities in multiple sclerosis: a 3-year longitudinal study

M Calabrese, F Rinaldi, D Seppi, A Favaretto… - Radiology, 2011 - pubs.rsna.org
Purpose To evaluate whether diffusion-tensor imaging can be combined with double
inversion recovery to improve the detection of structural changes occurring in the cortex of …

Thalamic involvement in multiple sclerosis: A diffusion‐weighted magnetic resonance imaging study

AJ Fabiano, J Sharma… - Journal of …, 2003 - Wiley Online Library
ABSTRACT Background and Purpose. Injury to deep gray matter structures in multiple
sclerosis (MS) has been suggested by recent neuroimaging and neuropathology studies …

Diffusion tensor imaging in multiple sclerosis at different final outcomes

O Andersen, A Hildeman, M Longfils… - Acta Neurologica …, 2018 - Wiley Online Library
Objectives Methods to evaluate the relative contributions of demyelination vs axonal
degeneration over the long‐term course of MS are urgently needed. We used magnetic …

Normal-appearing white and grey matter damage in MS: a volumetric and diffusion tensor MRI study at 3.0 Tesla

A Ceccarelli, MA Rocca, A Falini, P Tortorella… - Journal of …, 2007 - Springer
The aims of this study were to improve, using a 3.0 Tesla (T) scanner and diffusion tensor
(DT) magnetic resonance imaging (MRI) with sensitivity encoding, our understanding of: 1) …

A study of the mechanisms of normal-appearing white matter damage in multiple sclerosis using diffusion tensor imaging: evidence of Wallerian degeneration

O Ciccarelli, DJ Werring, GJ Barker, CM Griffin… - Journal of …, 2003 - Springer
Diffusion tensor imaging (DTI) investigates brain tissue microstructure in vivo. In multiple
sclerosis (MS) Wallerian degeneration of axons traversing focal lesions is a potential …