Local intra-arterial thrombolysis during mechanical thrombectomy for refractory large-vessel occlusion: adjunctive chemical enhancer of thrombectomy

SH Baik, C Jung, JY Kim, DW Shin… - American Journal …, 2021 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Data on adjunctive intra-arterial thrombolysis during
mechanical thrombectomy for refractory thrombus are sparse. The aim of this study was to …

Safety and efficacy of intra-arterial urokinase after failed, unsuccessful, or incomplete mechanical thrombectomy in anterior circulation large-vessel occlusion stroke

J Kaesmacher, S Bellwald, T Dobrocky… - JAMA …, 2020 - jamanetwork.com
Importance Achieving complete reperfusion is a key determinant of good outcome in
patients treated with mechanical thrombectomy (MT). However, data on treatments geared …

Recombinant tissue plasminogen activator in acute ischemic stroke patients receiving thrombectomy: standard or low dose therapy?

CH Lin, CH Liu, AYC Wang, YM Wu… - Current …, 2018 - ingentaconnect.com
Background: We compared the clinical outcomes of low and standard dose recombinant
tissue Plasminogen Activator (rtPA) treatment in Acute Ischemic Stroke (AIS) patients …

The end of tissue-type plasminogen activator's reign?

I Derraz - Stroke, 2022 - Am Heart Assoc
Mechanical thrombectomy is a highly effective treatment for acute ischemic stroke caused by
large-vessel occlusion in the anterior cerebral circulation, significantly increasing the …

Successful reperfusion with intravenous thrombolysis preceding mechanical thrombectomy in large-vessel occlusions

G Tsivgoulis, AH Katsanos, PD Schellinger… - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Although current guidelines advocate pretreatment with
intravenous thrombolysis (IVT) in all eligible patients with acute ischemic stroke with large …

Comparison of outcomes after mechanical thrombectomy alone or combined with intravenous thrombolysis and mechanical thrombectomy for patients with acute …

JH Choi, SH Im, KJ Lee, JS Koo, BS Kim, YS Shin - World Neurosurgery, 2018 - Elsevier
Background Whether intravenous thrombolysis (IVT) before mechanical thrombectomy (MT)
provides additional benefits remains controversial. We aimed to compare clinical and …

The role of intravenous thrombolysis before mechanical Thrombectomy: A subgroup analysis of the RESILIENT trial

GS Silva, MM Alves, FCD Barros, ME Frudit… - Journal of the …, 2024 - Elsevier
Background Randomized trials have recently evaluated the non-inferiority of direct
thrombectomy versus intravenous thrombolysis (IVT) followed by endovascular therapy in …

Bridging intravenous thrombolysis before mechanical thrombectomy for large artery occlusion may be detrimental with thrombus fragmentation

HJ Yi, JH Sung, DH Lee - Current Neurovascular Research, 2020 - ingentaconnect.com
Objective: We investigated whether intravenous thrombolysis (IVT) affected the outcomes
and complications of mechanical thrombectomy (MT), specifically focusing on thrombus …

Intra-arterial adjunctive medications for acute ischemic stroke during mechanical thrombectomy: a meta-analysis

VHE Chen, GKH Lee, CH Tan, AST Leow, YK Tan… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: In patients with acute ischemic stroke with large vessel occlusion,
the role of intra-arterial adjunctive medications (IAMs), such as urokinase, tPA (tissue-type …

[HTML][HTML] Thrombectomy versus combined thrombolysis and thrombectomy in patients with acute stroke

XU Tong, Y Wang, J Fiehler, CT Bauer, B Jia, X Zhang… - Stroke, 2021 - journals.lww.com
Background and Purpose: A recent randomized controlled trial DIRECT-MT (Direct Intra-
Arterial Thrombectomy to Revascularize AIS Patients With Large Vessel Occlusion Efficiently …