The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis

A Ceccarelli, JS Jackson, S Tauhid… - American Journal …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: VBM has been widely used to study GM atrophy in MS.
MS lesions lead to segmentation and registration errors that may affect the reliability of VBM …

Longitudinal gray matter changes in multiple sclerosis—differential scanner and overall disease‐related effects

K Bendfeldt, L Hofstetter, P Kuster, S Traud… - Human brain …, 2012 - Wiley Online Library
Voxel‐based morphometry (VBM) has been used repeatedly in single‐center studies to
investigate regional gray matter (GM) atrophy in multiple sclerosis (MS). In multi‐center …

Quantification of global cerebral atrophy in multiple sclerosis from 3T MRI using SPM: the role of misclassification errors

E Dell'Oglio, A Ceccarelli, BI Glanz… - Journal of …, 2015 - Wiley Online Library
ABSTRACT PURPOSE We tested the validity of a freely available segmentation pipeline to
measure compartmental brain volumes from 3T MRI in patients with multiple sclerosis (MS) …

VBM lesion detection depends on the normalization template: a study using simulated atrophy

S Shen, AJ Szameitat, A Sterr - Magnetic resonance imaging, 2007 - Elsevier
Structural neuroimaging studies are of great interest for neuroscientists, which are reflected
in the rising number of papers using voxel-based morphometry (VBM). One major step in …

Reliable brain morphometry from contrast‐enhanced T1w‐MRI in patients with multiple sclerosis

M Rebsamen, R McKinley, P Radojewski… - Human brain …, 2023 - Wiley Online Library
Brain morphometry is usually based on non‐enhanced (pre‐contrast) T1‐weighted MRI.
However, such dedicated protocols are sometimes missing in clinical examinations. Instead …

Voxel-wise assessment of progression of regional brain atrophy in relapsing-remitting multiple sclerosis

M Battaglini, A Giorgio, ML Stromillo… - Journal of the …, 2009 - Elsevier
OBJECTIVE: To perform voxel-wise assessments of regional brain atrophy state and rate in
subjects with relapsing–remitting (RR) multiple sclerosis (MS). BACKGROUND: Recently …

Segmentation of brain magnetic resonance images for measurement of gray matter atrophy in multiple sclerosis patients

K Nakamura, E Fisher - Neuroimage, 2009 - Elsevier
Multiple sclerosis (MS) affects both white matter and gray matter (GM). Measurement of GM
volumes is a particularly useful method to estimate the total extent of GM tissue damage …

Spatial normalization of multiple sclerosis brain MRI data depends on analysis method and software package

S Pirzada, MN Uddin, TD Figley, J Kornelsen… - Magnetic resonance …, 2020 - Elsevier
Background Spatially normalizing brain MRI data to a template is commonly performed to
facilitate comparisons between individuals or groups. However, the presence of multiple …

The effect of hypointense white matter lesions on automated gray matter segmentation in multiple sclerosis

R Gelineau‐Morel, V Tomassini… - Human brain …, 2012 - Wiley Online Library
Previous imaging studies assessing the relationship between white matter (WM) damage
and matter (GM) atrophy have raised the concern that Multiple Sclerosis (MS) WM lesions …

[HTML][HTML] MRI pattern recognition in multiple sclerosis normal-appearing brain areas

M Weygandt, K Hackmack, C Pfüller… - PloS one, 2011 - journals.plos.org
Objective Here, we use pattern-classification to investigate diagnostic information for
multiple sclerosis (MS; relapsingremitting type) in lesioned areas, areas of normalappearing …