CT perfusion mean transit time maps optimally distinguish benign oligemia from true “at-risk” ischemic penumbra, but thresholds vary by postprocessing technique

S Kamalian, S Kamalian, AA Konstas… - American journal …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Various CTP parameters have been used to identify
ischemic penumbra. The purpose of this study was to determine the optimal CTP parameter …

Recognizing false ischemic penumbras in CT brain perfusion studies

AC Best, NR Acosta, JE Fraser, MT Borges, KE Brega… - Radiographics, 2012 - pubs.rsna.org
Computed tomography (CT) plays a pivotal role in the diagnosis of acute stroke and in
treatment decision making. CT perfusion imaging performed with intravenous iodinated …

Optimal perfusion computed tomographic thresholds for ischemic core and penumbra are not time dependent in the clinically relevant time window

Y Qiao, G Zhu, J Patrie, W Xin, P Michel, A Eskandari… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—This study aims to determine whether perfusion computed
tomographic (PCT) thresholds for delineating the ischemic core and penumbra are time …

Differences in CT perfusion summary maps for patients with acute ischemic stroke generated by 2 software packages

F Fahmi, HA Marquering… - American Journal …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Although CT perfusion is a promising tool to support
treatment decisions for patients with acute ischemic stroke, it still lacks a standardized …

[HTML][HTML] CT-perfusion stroke imaging: a threshold free probabilistic approach to predict infarct volume compared to traditional ischemic thresholds

F Flottmann, G Broocks, TD Faizy, M Ernst… - Scientific Reports, 2017 - nature.com
The aim was to evaluate a novel method of threshold-free prediction of brain infarct from
computed tomography perfusion (CTP) imaging in comparison to conventional ischemic …

Improved Prediction of Final Infarct Volume Using Bolus Delay–Corrected Perfusion-Weighted MRI: Implications for the Ischemic Penumbra

SE Rose, AL Janke, M Griffin, S Finnigan, JB Chalk - Stroke, 2004 - Am Heart Assoc
Background and Purpose—Magnetic resonance imaging (MRI)-based perfusion measures
using dynamic susceptibility contrast are extremely useful for identification of ischemic …

Perfusion-CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke

M Wintermark, AE Flanders, B Velthuis, R Meuli… - Stroke, 2006 - Am Heart Assoc
Background and Purpose—Different definitions have been proposed to define the ischemic
penumbra from perfusion-CT (PCT) data, based on parameters and thresholds tested only in …

Reliability of CT perfusion in the evaluation of the ischaemic penumbra

JE Alves, Â Carneiro, J Xavier - The neuroradiology journal, 2014 - journals.sagepub.com
CT perfusion (CTP) is part of the initial evaluation of stroke patients, allowing differentiation
between infarcted tissue and the ischaemic penumbra and helping in the selection of …

Clinical use of computed tomographic perfusion for the diagnosis and prediction of lesion growth in acute ischemic stroke

BN Huisa, WP Neil, R Schrader, M Maya… - Journal of Stroke and …, 2014 - Elsevier
Background Computed tomography perfusion (CTP) mapping in research centers correlates
well with diffusion-weighted imaging (DWI) lesions and may accurately differentiate the …

Identification of penumbra and infarct in acute ischemic stroke using computed tomography perfusion–derived blood flow and blood volume measurements

BD Murphy, AJ Fox, DH Lee, DJ Sahlas, SE Black… - Stroke, 2006 - Am Heart Assoc
Background and Purpose—We investigated whether computed tomography (CT) perfusion–
derived cerebral blood flow (CBF) and cerebral blood volume (CBV) could be used to …