Whole-brain N-acetylaspartate level and cognitive performance in HIV infection

SH Patel, M Inglese, G Glosser… - American journal …, 2003 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: In the brain of HIV-infected patients, proton MR
spectroscopic studies are typically used to examine small volumes of tissue with single …

Prospective utility of cerebral proton magnetic resonance spectroscopy in monitoring HIV infection and its associated neurological impairment

JR McCONNELL, S Swindells, CS Ong… - AIDS research and …, 1994 - liebertpub.com
Neurological manifestations of HIV disease occur in most adults and children with AIDS.
Many of those affected will inevitably suffer clinical neurological deficits involving mental …

7T brain MRS in HIV infection: correlation with cognitive impairment and performance on neuropsychological tests

M Mohamed, PB Barker… - American Journal of …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Validated neuroimaging markers of HIV-associated
neurocognitive disorder in patients on antiretroviral therapy are urgently needed for clinical …

N-acetylaspartate reductions measured by 1H MRSI in cognitively impaired HIV-seropositive individuals

DJ Meyerhoff, S MacKay, N Poole, WP Dillon… - Magnetic resonance …, 1994 - Elsevier
We used magnetic resonance imaging (MRI) and water-suppressed proton MR
spectroscopic imaging (1 H MRSI) to study the effects of human immunodeficiency virus …

Reduced brain N‐acetylaspartate suggests neuronal loss in cognitively impaired human immunodeficiency virus‐seropositive individuals: In vivo 1H magnetic …

DJ Meyerhoff, S MacKay, L Bachman, N Poole… - Neurology, 1993 - AAN Enterprises
We used magnetic resonance imaging (MRI) and water-suppressed proton magnetic
resonance spectroscopic imaging to study the effects of human immunodeficiency virus …

[HTML][HTML] Cortical NAA deficits in HIV infection without dementia: influence of alcoholism comorbidity

A Pfefferbaum, E Adalsteinsson… - …, 2005 - nature.com
Alcoholism comorbidity is highly prevalent in individuals infected with human
immunodeficiency virus (HIV). Each condition is known to affect brain structure, function, and …

Deep gray matter structures in HIV infection: a proton MR spectroscopic study.

DJ Meyerhoff, MW Weiner… - American journal of …, 1996 - Am Soc Neuroradiology
PURPOSE To evaluate the effects of human immunodeficiency virus (HIV) infection on
proton metabolites in brain regions carrying the heaviest HIV load. METHODS We used two …

Longitudinal whole-brain N-acetylaspartate concentration in healthy adults

DJ Rigotti, II Kirov, B Djavadi, N Perry… - American journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Although NAA is often used as a marker of neural integrity
and health in different neurologic disorders, the temporal behavior of WBNAA is not well …

Factor analysis of proton MR spectroscopic imaging data in HIV infection: metabolite-derived factors help identify infection and dementia

MA Mohamed, MR Lentz, V Lee, EF Halpern, N Sacktor… - Radiology, 2010 - pubs.rsna.org
Purpose To develop a relevant pathophysiologic model of human immunodeficiency virus
(HIV)-associated dementia by studying regional variations in metabolite levels measured …

Proton MRS and quantitative MRI assessment of the short term neurological response to antiretroviral therapy in AIDS

ID Wilkinson, S Lunn, KA Miszkiel, RF Miller… - Journal of Neurology …, 1997 - jnnp.bmj.com
OBJECTIVE To investigate MRI and proton spectroscopy changes in five patients with HIV
associated dementia complex (HADC) treated with antiretroviral therapy. METHODS Three …