In many pathophysiologic situations, including brain neoplasms, neurodegenerative
disease, and chronic and acute ischemia, an imbalance exists between oxygen tissue …

Quantitative blood oxygenation level dependent approaches have been designed to obtain
quantitative oxygenation information using MRI. A mathematical model is usually fitted to the …

A quantitative estimate of cerebral blood oxygen saturation is of critical importance in the
investigation of cerebrovascular disease. While positron emission tomography can map in …

A quantitative estimate of cerebral blood oxygen saturation is of critical importance in the
investigation of cerebrovascular disease because of the fact that it could potentially provide …

Metabolic markers of baseline brain oxygenation and tissue perfusion have an important
role to play in the early identification of ischaemic tissue in acute stroke. Although well …

The ability to image the ischemic penumbra during hyperacute stroke promises to identify
patients who may benefit from treatment intervention beyond population-defined therapeutic …

Mapping the ischemic penumbra (ie, the neurophysio-logically silent but still viable ischemic
tissue) is increasingly part of routine assessment in suspected acute stroke, although …

Calibrated blood oxygenation level dependent (BOLD) imaging, a technique used to
measure changes in cerebral O2 metabolism, depends on an accurate model of how the …

The blood oxygenation level‐dependent (BOLD) phenomenon has profoundly
revolutionized neuroscience, with applications ranging from normal brain development and …

Blood oxygenation level‐dependent (BOLD) contrast MRI is a potential method for a
physiological characterization of tissue beyond mere morphological representation. The …