Dilatation of the Virchow-Robin space is a sensitive indicator of cerebral microvascular disease: study in elderly patients with dementia

TF Patankar, D Mitra, A Varma… - American Journal …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Virchow-Robin spaces (VRSs) are CSF spaces that
accompany blood vessels as they perforate the brain substance. Dilatation of VRS is …

Assessment of the Virchow-Robin Spaces in Alzheimer disease, mild cognitive impairment, and normal aging, using high-field MR imaging

W Chen, X Song, Y Zhang… - American Journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: VRSs are the perivascular spaces surrounding the deep
perforating arteries in the brain. Although VRS variations with age and disease pathologies …

Visible Virchow-Robin spaces on magnetic resonance imaging of Alzheimer's disease patients and normal elderly from the Sunnybrook Dementia Study

J Ramirez, C Berezuk, AA McNeely… - Journal of …, 2015 - content.iospress.com
Background: Visible Virchow-Robin spaces (VRS) are commonly used markers for small
vessel disease in aging and dementia. Objective: However, as previous reports were based …

Virchow-Robin spaces relate to cerebral small vessel disease severity

RPW Rouhl, RJ Van Oostenbrugge, ILH Knottnerus… - Journal of …, 2008 - Springer
Abstract Background and purpose Virchow-Robin spaces (VRs) are perivascular spaces
surrounding the deep perforating brain arteries. VRs dilatation is pathologic, and it could be …

Perivascular spaces in MS patients at 7 Tesla MRI: a marker of neurodegeneration?

ID Kilsdonk, MD Steenwijk… - Multiple Sclerosis …, 2015 - journals.sagepub.com
Background: Virchow-Robin spaces (VRS) are associated with vascular and
neurodegenerative disease. In multiple sclerosis (MS), VRS have been associated with …

Severity of dilated Virchow-Robin spaces is associated with age, blood pressure, and MRI markers of small vessel disease: a population-based study

YC Zhu, C Tzourio, A Soumaré, B Mazoyer, C Dufouil… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—Little is known about the risk factors of dilated Virchow-Robin
spaces (dVRS) and their relation with other markers of brain small vessel disease. We …

Frequency and location of dilated Virchow-Robin spaces in elderly people: a population-based 3D MR imaging study

YC Zhu, C Dufouil, B Mazoyer… - American Journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: dVRS have been previously associated with aging and
cerebrovascular diseases. However, little is known about their prevalence and topographic …

Virchow-Robin spaces on magnetic resonance images: normative data, their dilatation, and a review of the literature

S Groeschel, WK Chong, R Surtees, F Hanefeld - Neuroradiology, 2006 - Springer
Abstract Introduction Virchow-Robin spaces (VRS) are perivascular spaces in the brain and
can be visualized on magnetic resonance images (MRI). We attempt to provide a better …

Dilated perivascular spaces in the Basal Ganglia are a biomarker of small-vessel disease in a very elderly population with dementia

TP Hansen, J Cain, O Thomas… - American Journal of …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Dilated perivascular spaces have been shown to be a
specific biomarker of cerebral small-vessel disease in young patients with dementia. Our …

Large perivascular spaces visible on magnetic resonance imaging, cerebral small vessel disease progression, and risk of dementia: the age, gene/environment …

J Ding, S Sigurðsson, PV Jónsson, G Eiriksdottir… - JAMA …, 2017 - jamanetwork.com
Importance With advancing age, an increased visibility of perivascular spaces (PVSs) on
magnetic resonance imaging (MRI) is hypothesized to represent impaired drainage of …