1H MR spectroscopic characteristics of kernicterus: a possible metabolic signature

WK Oakden, AM Moore, S Blaser… - American journal of …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: MR examination of infants with kernicterus shows
abnormal changes in signal intensity in various parts of the brain, including the globus …

[HTML][HTML] Brain magnetic resonance imaging and magnetic resonance spectroscopy findings of children with kernicterus

S Sarı, A Yavuz, A Batur, A Bora… - Polish Journal of …, 2015 - ncbi.nlm.nih.gov
Background The term kernicterus, or bilirubin encephalopathy, is used to describe
pathological bilirubin staining of the basal ganglia, brain stem, and cerebellum, and is …

Assessing the risk of kernicterus using nuclear magnetic resonance

C Palmer, MB Smith - Clinics in perinatology, 1990 - Elsevier
Multiple factors may contribute to bilirubin neurotoxicity, and serum bilirubin levels alone are
poor predictors of brain injury; however, bilirubin impairs cerebral energy metabolism in a …

Clinical and cranial magnetic resonance imaging (MRI) findings of 21 patients with serious hyperbilirubinemia

S Katar, HO Akay, M Taskesen… - Journal of child …, 2008 - journals.sagepub.com
This study aims to compare neurological examination and cranial magnetic resonance
imaging (MRI) findings in patients with serious hyperbilirubinemia. Twenty-one serious …

New autopsy findings in different brain regions of a preterm neonate with kernicterus: neurovascular alterations and up-regulation of efflux transporters

MA Brito, P Pereira, C Barroso, E Aronica, D Brites - Pediatric neurology, 2013 - Elsevier
Background Kernicterus is an irreversible brain damage caused by bilirubin deposition in
selective brain regions. Sick and preterm infants with hyperbilirubinemia are particularly …

Definition of the clinical spectrum of kernicterus and bilirubin-induced neurologic dysfunction (BIND)

SM Shapiro - Journal of perinatology, 2005 - nature.com
Kernicterus, currently used to describe both the neuropathology of bilirubin-induced brain
injury and its associated clinical findings, is a complex syndrome. The neurobiology of …

Neurological complications of kernicterus

SF AlOtaibi, S Blaser, DL MacGregor - Canadian journal of …, 2005 - cambridge.org
Objective and Background: Prevention of bilirubin encephalopathy relies on the detection of
newborns who are at risk of developing serious hyperbilirubinemia. The objective of this …

Magnetic resonance imaging in three children with kernicterus

S Sugama, A Soeda, Y Eto - Pediatric neurology, 2001 - Elsevier
The incidence of kernicterus has been greatly reduced by effective monitoring and treatment
for hyperbilirubinemia. Findings on magnetic resonance imaging (MRI) in patients with …

[HTML][HTML] MRI of bilirubin encephalopathy (kernicterus): A case series of 4 patients from Sub-Saharan Africa, May 2017

GA Neknek, K Woldemichael, A Moges… - Radiology Case …, 2018 - Elsevier
Characteristic magnetic resonance imaging (MRI) findings in patients with chronic
kernicterus are bilateral and symmetric T2-weighted hyperintensities in the globus pallidus …

Bilirubin metabolism and kernicterus

GR Gourley - Advances in pediatrics, 1997 - Elsevier
Neonatal jaundice continues to be a common problem. Kernicterus, although rare, continues
to be a very real concern in both full-term and preterm infants. The diagnosis of kernicterus …