Myelitis and optic neuritis are prototypic clinical presentations of both multiple sclerosis and
neuromyelitis optica. Once considered a subtype of multiple sclerosis, neuromyelitis optica …

Early identification of neuromyelitis optica allows aggressive acute and prophylactic relapse
management aimed at preventing disability. Since the discovery of pathogenic aquaporin-4 …

Neuromyelitis optica (NMO) is a severe, inflammatory demyelinating disorder of the central
nervous system (CNS) that was first described by Devic in 1894. NMO is characterized by …

Clinical, radiologic, and immunologic features distinguish neuromyelitis optica from other
severe cases of multiple sclerosis. NMO-IgG is the first specific marker for a central nervous …

The traditional view of neuromyelitis optica (NMO) as a monophasic inflammatory disorder
that affects both the optic nerves and the spinal cord is expanding. Over the last decade, a …

BACKGROUND AND PURPOSE: Conventional MR imaging typically yields normal images
of the brain or indicates lesions in areas of high aquaporin expression in patients with …

Background: Neuromyelitis optica (NMO) is an uncommon CNS demyelinating syndrome
often mistaken for severe multiple sclerosis (MS). Several clinical, laboratory, and …

Introduction Neuromyelitis optica (NMO) is a severe demyelinating disease that
preferentially involves spinal cord and optic nerve. It is part of a spectrum of neurological …

Neuromyelitis optica (NMO) is characterized by severe optic neuritis and transverse myelitis.
The relationship of NMO to multiple sclerosis (MS) has long been debated, but NMO has …

Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disease of the central
nervous system (CNS) associated with antibodies to aquaporin-4 (AQP4), which has distinct …