Retention of gadolinium-based contrast agents in multiple sclerosis: retrospective analysis of an 18-year longitudinal study

Y Forslin, S Shams, F Hashim… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Gadolinium-based contrast agents have been associated
with lasting high T1-weighted signal intensity in the dentate nucleus and globus pallidus …

Gadolinium retention in the brain: an MRI relaxometry study of linear and macrocyclic gadolinium-based contrast agents in multiple sclerosis

Y Forslin, J Martola, Å Bergendal… - American Journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Brain gadolinium retention is consistently reported for
linear gadolinium-based contrast agents, while the results for macrocyclics are contradictory …

Increasing signal intensity within the dentate nucleus and globus pallidus on unenhanced T1W magnetic resonance images in patients with relapsing-remitting …

DA Stojanov, A Aracki-Trenkic, S Vojinovic… - European …, 2016 - Springer
Objective To evaluate correlation between cumulative dose of gadobutrol and signal
intensity (SI) within dentate nucleus and globus pallidus on unenhanced T1-weighted …

Progressive T1 shortening of the dentate nucleus in patients with multiple sclerosis: result of multiple administrations of linear gadolinium contrast agents versus …

A Malhotra, B LeSar, X Wu, D Durand… - American Journal of …, 2018 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this article is to study the effect of the administration of multiple
IV doses of gadolinium-based contrast agent on the intrinsic T1 hyperintensity in the dentate …

Cumulative gadodiamide administration leads to brain gadolinium deposition in early MS

R Zivadinov, N Bergsland, J Hagemeier… - Neurology, 2019 - AAN Enterprises
Objective Frequent administration of gadolinium-based contrast agents in multiple sclerosis
(MS) may increase signal intensity (SI) unenhanced T1-weighted imaging MRI throughout …

Diffusion-weighted imaging of the dentate nucleus after repeated application of gadolinium-based contrast agents in multiple sclerosis

P Eisele, K Szabo, A Ebert, A Radbruch… - Magnetic Resonance …, 2019 - Elsevier
Objective Over the last years several studies reported an increased signal intensity (SI) of
the dentate nucleus (DN) on unenhanced T1-weighted images after repeated application of …

[HTML][HTML] Lack of increased signal intensity in the dentate nucleus after repeated administration of a macrocyclic contrast agent in multiple sclerosis: an observational …

P Eisele, A Alonso, K Szabo, A Ebert, M Ong… - Medicine, 2016 - journals.lww.com
Recently, several studies reported increased signal intensity (SI) in the dentate nucleus (DN)
after repeated application of gadolinium-based contrast agents (GBCAs), suggesting a …

Gadopentetate but not gadobutrol accumulates in the dentate nucleus of multiple sclerosis patients

L Schlemm, C Chien, J Bellmann-Strobl… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Background: Previous studies have postulated an association between dentate nucleus T1
hyperintensity and multiple sclerosis (MS)-related progressive neurodegeneration …

Effects of serial macrocyclic-based contrast materials gadoterate meglumine and gadobutrol administrations on gadolinium-related dentate nuclei signal increases in …

A Splendiani, M Perri, C Marsecano, V Vellucci… - La radiologia …, 2018 - Springer
Purpose To perform T1 signal intensity (SI) measurements in the dentate nuclei of adult
patients with confirmed multiple sclerosis (MS) after serial administrations of the macrocyclic …

High signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images: relationship with increasing cumulative dose of a …

T Kanda, K Ishii, H Kawaguchi, K Kitajima, D Takenaka - Radiology, 2014 - pubs.rsna.org
Purpose To explore any correlation between the number of previous gadolinium-based
contrast material administrations and high signal intensity (SI) in the dentate nucleus and …