Focal low and global high permeability predict the possibility, risk, and location of hemorrhagic transformation following intra-arterial thrombolysis therapy in acute …

Y Li, Y Xia, H Chen, N Liu, A Jackson… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The contrast volume transfer coefficient (K trans), which
reflects blood-brain barrier permeability, is influenced by circulation and measurement …

Mismatch of low perfusion and high permeability predicts hemorrhagic transformation region in acute ischemic stroke patients treated with intra-arterial thrombolysis

H Chen, N Liu, Y Li, M Wintermark, A Jackson, B Wu… - Scientific reports, 2016 - nature.com
This study sought to determine whether the permeability related parameter Ktrans, derived
from computed tomography perfusion (CTP) imaging, can predict hemorrhagic …

Computed tomography perfusion derived blood-brain barrier permeability does not yet improve prediction of hemorrhagic transformation

AD Horsch, E Bennink, T van Seeters… - Cerebrovascular …, 2018 - karger.com
Introduction: Hemorrhagic transformation (HT) in acute ischemic stroke can occur as a result
of reperfusion treatment. While withholding treatment may be warranted in patients with …

CT permeability imaging predicts clinical outcomes in acute ischemic stroke patients treated with intra-arterial thrombolytic therapy

N Liu, H Chen, B Wu, Y Li, M Wintermark… - Molecular …, 2017 - Springer
In this study, we determined whether a prediction of final infarct volume (FIV) and clinical
outcomes in patients with an acute stroke is improved by using a contrast transfer coefficient …

Blood-brain barrier permeability assessed by perfusion computed tomography predicts hemorrhagic transformation in acute reperfusion therapy

T Kim, J Koo, S Kim, IU Song, SW Chung, KS Lee - Neurological Sciences, 2018 - Springer
Hemorrhagic transformation (HT) is one of the most feared complications of acute
recanalization therapies. The aim of this study was to evaluate whether blood-brain barrier …

High-permeability region size on perfusion CT predicts hemorrhagic transformation after intravenous thrombolysis in stroke

J Puig, G Blasco, P Daunis-i-Estadella… - PLoS …, 2017 - journals.plos.org
Objective Blood-brain barrier (BBB) permeability has been proposed as a predictor of
hemorrhagic transformation (HT) after tissue plasminogen activator (tPA) administration; …

Permeability measures predict hemorrhagic transformation after ischemic stroke

A Bivard, T Kleinig, L Churilov, C Levi, L Lin… - Annals of …, 2020 - Wiley Online Library
Objective We sought to examine the diagnostic utility of existing predictors of any
hemorrhagic transformation (HT) and compare them with new perfusion imaging …

Blood–brain barrier leakage and hemorrhagic transformation: The Reperfusion Injury in Ischemic StroKe (RISK) study

F Arba, B Piccardi, V Palumbo, S Biagini… - European Journal of …, 2021 - Wiley Online Library
Background and purpose In patients with acute ischemic stroke treated with reperfusion
therapy we aimed to evaluate whether pretreatment blood–brain barrier (BBB) leakage is …

Measuring elevated microvascular permeability and predicting hemorrhagic transformation in acute ischemic stroke using first-pass dynamic perfusion CT imaging

K Lin, KS Kazmi, M Law, J Babb… - American Journal …, 2007 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Hemorrhagic transformation (HT) can be a devastating
complication of acute ischemic stroke (AIS). The purpose of this study was to determine …

Thrombus permeability on dynamic CTA predicts good outcome after reperfusion therapy

Z Chen, F Shi, X Gong, R Zhang… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Thrombus permeability assessed on conventional CTA is
associated with neurologic outcome in patients with acute ischemic stroke. We aimed to …