BACKGROUND AND PURPOSE: Spinal cord atrophy is a common and clinically relevant
characteristic in multiple sclerosis. We aimed to perform a multicenter validation study of …

Background In multiple sclerosis (MS), recent work suggests that cervical cord atrophy is
more consistently correlated with physical disability than brain white matter lesion load and …

Background The reliable and efficient measurement of spinal cord atrophy is of growing
interest in monitoring disease progression in multiple sclerosis (MS). Methods We compared …

Background Spinal cord atrophy provides a clinically relevant metric for monitoring MS.
However, the spinal cord is imaged far less frequently than brain due to artefacts and …

BACKGROUND AND PURPOSE: Evidence is mounting that spinal cord atrophy significantly
correlates with disability in patients with multiple sclerosis (MS). The purpose of this work …

Background: Considerable spinal cord (SC) atrophy occurs in multiple sclerosis (MS). While
MRI-based techniques for SC cross-sectional area (CSA) quantification have improved over …

Introduction Atrophy of the spinal cord is known to occur in multiple sclerosis (MS). The
mean upper cervical cord area (MUCCA) can be used to measure this atrophy. Currently …

Purpose To identify an improved method for measuring spinal cord cross‐sectional area
(CSA) using magnetic resonance imaging (MRI) in multiple sclerosis (MS). Materials and …

Object: Automatic accurate measurement techniques are needed to increase reproducibility
in the quantification of cervical cord area (CCA) with magnetic resonance (MR) imaging in …

Purpose To measure accurately the upper cervical cord cross‐sectional area (CSA) in
patients with relapsing remitting multiple sclerosis (RRMS), and normal control subjects, to …