Hypoxic-ischemic brain injury in the neonatal rat model: relationship between lesion size at early MR imaging and irreversible infarction

Y Wang, PT Cheung, GX Shen… - American journal …, 2006 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: By using a neonatal rat hypoxia-ischemia (HI) model, we
studied the relationship between lesion volume—measured by diffusion-weighted imaging …

Comparing diffusion-weighted and T2-weighted MR imaging for the quantification of infarct size in a neonatal rat hypoxic–ischemic model at 24 h post-injury

Y Wang, PT Cheung, GX Shen, I Bhatia, EX Wu… - International journal of …, 2007 - Elsevier
PURPOSE: In a neonatal rat model of hypoxic–ischemic (HI) brain injury, using T2-weighted
imaging (T2WI) and diffusion-weighted imaging (DWI), we aim to determine the best MRI …

Cerebral ischemic hypoxia: discrepancy between apparent diffusion coefficients and histologic changes in rats

N Miyasaka, T Kuroiwa, FY Zhao, T Nagaoka… - Radiology, 2000 - pubs.rsna.org
PURPOSE: To compare the apparent diffusion coefficients (ADCs) and histologic changes in
young rats subjected to cerebral ischemic hypoxia (IH). MATERIALS AND METHODS …

MRI evaluation and functional assessment of brain injury after hypoxic ischemia in neonatal mice

U Ådén, V Dahlberg, BB Fredholm, LJ Lai, Z Chen… - Stroke, 2002 - Am Heart Assoc
Background and Purpose—Severe perinatal asphyxia is an important cause of brain injury
in the newborn infant. We examined early events after hypoxic ischemia (HI) in the 7-day-old …

Evolution of magnetic resonance imaging changes associated with cerebral hypoxia-ischemia and a relatively selective white matter injury in neonatal rats

S Meng, MIN Qiao, K Scobie, B Tomanek, UI Tuor - Pediatric research, 2006 - nature.com
We hypothesized that a combination of quantitative magnetic resonance imaging (MRI)
sequences would detect a differential evolution of hypoxic-ischemic changes in white matter …

Magnetic resonance imaging of hypoxic-ischemic brain injury in the neonatal rat

BC Albensi, MP Schweizer, TM Rarick… - Investigative …, 1998 - journals.lww.com
RATIONALE AND OBJECTIVES. Magnetic resonance (MR) imaging was used for the in vivo
evaluation of bihemispheric hypoxic-ischemic (HI) injury in the neonatal rat. METHODS …

Diffusion characteristics associated with neuronal injury and glial activation following hypoxia‐ischemia in the immature brain

GA Lodygensky, T West, MD Moravec… - Magnetic resonance …, 2011 - Wiley Online Library
To identify quantitative MRI indices of injury in the brain following neonatal hypoxic‐
ischemic brain injury, we subjected mouse pups to hypoxia‐ischemia on postnatal day 7 …

Mild hypoxic-ischemic injury in the neonatal rat brain: longitudinal evaluation of white matter using diffusion tensor MR imaging

S Wang, EX Wu, K Cai, HF Lau… - American journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Selective white matter (WM) damage is a known sequela
of mild hypoxic-ischemic (HI) injury in the neonatal rat model. The aim of this study was to …

Magnetic resonance imaging of brain edema in the neonatal rat: a comparison of short and long term hypoxia-ischemia

H Rumpel, R Buchli, J Gehrmann, A Aguzzi, O Illi… - Pediatric …, 1995 - nature.com
Diffusion-weighted and transversal relaxation time (T 2)-weighted magnetic resonance
imaging were used to study the relationship between the duration of hypoxia-ischemia …

Effect of the reperfusion after cerebral ischemia in neonatal rats using MRI monitoring

S Fau, C Po, B Gillet, S Sizonenko, J Mariani… - Experimental …, 2007 - Elsevier
Cerebral hypoxia–ischemia is an important cause of brain injury in the newborn infant. Our
purpose was to study magnetic resonance (MR) imaging changes in P7 rat brains submitted …