Quantitative susceptibility mapping and R2* measured changes during white matter lesion development in multiple sclerosis: myelin breakdown, myelin debris …
Y Zhang, SA Gauthier, A Gupta… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Quantitative susceptibility mapping and R2* are sensitive
to myelin and iron changes in multiple sclerosis lesions. This study was designed to …
to myelin and iron changes in multiple sclerosis lesions. This study was designed to …
In vivo 7T MR quantitative susceptibility mapping reveals opposite susceptibility contrast between cortical and white matter lesions in multiple sclerosis
W Bian, E Tranvinh, T Tourdias… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Magnetic susceptibility measured with quantitative
susceptibility mapping has been proposed as a biomarker for demyelination and …
susceptibility mapping has been proposed as a biomarker for demyelination and …
Quantitative susceptibility mapping of time-dependent susceptibility changes in multiple sclerosis lesions
BACKGROUND AND PURPOSE: MR imaging studies have demonstrated that magnetic
susceptibility in multiple sclerosis lesions is dependent on lesion age. The objective of this …
susceptibility in multiple sclerosis lesions is dependent on lesion age. The objective of this …
Quantifying the susceptibility variation of normal-appearing white matter in multiple sclerosis by quantitative susceptibility mapping
W Chen, Y Zhang, K Mu, C Pan… - American Journal of …, 2017 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study is to evaluate the magnetic susceptibility of normal-
appearing white matter (NAWM) in patients with multiple sclerosis (MS) using quantitative …
appearing white matter (NAWM) in patients with multiple sclerosis (MS) using quantitative …
Multiple sclerosis: improved identification of disease-relevant changes in gray and white matter by using susceptibility-based MR imaging
Purpose To evaluate the potential of quantitative susceptibility (QS) and R2* mapping as
surrogate biomarkers of clinically relevant, age-adjusted demyelination and iron deposition …
surrogate biomarkers of clinically relevant, age-adjusted demyelination and iron deposition …
Lesion heterogeneity on high-field susceptibility MRI is associated with multiple sclerosis severity
BACKGROUND AND PURPOSE: Susceptibility MR imaging contrast variations reflect
alterations in brain iron and myelin content, making this imaging tool relevant to studies of …
alterations in brain iron and myelin content, making this imaging tool relevant to studies of …
[HTML][HTML] The distributional characteristics of multiple sclerosis lesions on quantitative susceptibility mapping and their correlation with clinical severity
Z Guo, L Long, W Qiu, T Lu, L Zhang, Y Shu… - Frontiers in …, 2021 - frontiersin.org
Background: Multiple sclerosis (MS) patients have a wide spectrum of severity and
responses to therapy; the personalization of treatment relies on sensitive and specific …
responses to therapy; the personalization of treatment relies on sensitive and specific …
Quantitative susceptibility mapping (QSM) of white matter multiple sclerosis lesions: interpreting positive susceptibility and the presence of iron
C Wisnieff, S Ramanan, J Olesik… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose Within multiple sclerosis (MS) lesions iron is present in chronically activated
microglia. Thus, iron detection with MRI might provide a biomarker for chronic inflammation …
microglia. Thus, iron detection with MRI might provide a biomarker for chronic inflammation …
Combining quantitative susceptibility mapping with automatic zero reference (QSM0) and myelin water fraction imaging to quantify iron-related myelin damage in …
Y Yao, TD Nguyen, S Pandya… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: A hyperintense rim on susceptibility in chronic MS lesions
is consistent with iron deposition, and the purpose of this study was to quantify iron-related …
is consistent with iron deposition, and the purpose of this study was to quantify iron-related …
Quantitative susceptibility mapping of multiple sclerosis lesions at various ages
W Chen, SA Gauthier, A Gupta, J Comunale, T Liu… - Radiology, 2014 - pubs.rsna.org
Purpose To assess multiple sclerosis (MS) lesions at various ages by using quantitative
susceptibility mapping (QSM) and conventional magnetic resonance (MR) imaging …
susceptibility mapping (QSM) and conventional magnetic resonance (MR) imaging …
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