Determining the degree of dopaminergic denervation based on the loss of nigral hyperintensity on SMWI in parkinsonism
BACKGROUND AND PURPOSE: Nigrostriatal dopaminergic function in patients with
Parkinson disease can be assessed using 123I-2β-carbomethoxy-3β-(4-iodophenyl)-N-(3 …
Parkinson disease can be assessed using 123I-2β-carbomethoxy-3β-(4-iodophenyl)-N-(3 …
[HTML][HTML] Deep learning regressor model based on nigrosome MRI in Parkinson syndrome effectively predicts striatal dopamine transporter-SPECT uptake
Purpose Nigrosome imaging using susceptibility-weighted imaging (SWI) and dopamine
transporter imaging using 123I-2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl) …
transporter imaging using 123I-2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl) …
[HTML][HTML] Nigral volumetric and microstructural measures in individuals with scans without evidence of dopaminergic deficit
Introduction Striatal dopamine transporter (DAT) imaging using 123I-ioflupane single photon
positron emitted computed tomography (SPECT)(DaTScan, GE) identifies 5− 20% of newly …
positron emitted computed tomography (SPECT)(DaTScan, GE) identifies 5− 20% of newly …
Initial diagnostic workup of parkinsonism: Dopamine transporter positron emission tomography versus susceptibility map-weighted imaging at 3T
Abstract Background and Purpose Evaluation of dorsal nigral hyperintensity on MRI can
help detect nigrostriatal degeneration. We aimed to compare the diagnostic performance …
help detect nigrostriatal degeneration. We aimed to compare the diagnostic performance …
Automated assessment of the substantia nigra on susceptibility map-weighted imaging using deep convolutional neural networks for diagnosis of Idiopathic …
DH Shin, H Heo, S Song, NY Shin, Y Nam… - Parkinsonism & Related …, 2021 - Elsevier
Objectives Despite its use in determining nigrostriatal degeneration, the lack of a consistent
interpretation of nigrosome 1 susceptibility map-weighted imaging (SMwI) limits its …
interpretation of nigrosome 1 susceptibility map-weighted imaging (SMwI) limits its …
MRI of nigrosome‐1: a potential triage tool for patients with suspected parkinsonism
Abstract Background and Purpose Susceptibility‐weighted imaging (SWI) of nigrosome‐1 is
an emerging and clinically applicable imaging marker for parkinsonism, which can be …
an emerging and clinically applicable imaging marker for parkinsonism, which can be …
Preserved Extrastriatal 123I-FP-CIT Binding in Scans Without Evidence of Dopaminergic Deficit (SWEDD)
Purpose Scans without evidence of dopaminergic deficit (SWEDD) have been initially
described in a minority of subjects with suspected Parkinson's disease (PD). Although a …
described in a minority of subjects with suspected Parkinson's disease (PD). Although a …
Dorsal-to-ventral shift in midbrain dopaminergic projections and increased thalamic/raphe serotonergic function in early Parkinson disease
J Joutsa, J Johansson, M Seppänen… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Loss of nigrostriatal neurons leading to dopamine depletion in the dorsal striatum is the
pathologic hallmark of Parkinson disease contributing to the primary motor symptoms of the …
pathologic hallmark of Parkinson disease contributing to the primary motor symptoms of the …
Differential alterations of dopamine transporter in the striatum and midbrain in patients with parkinsonian syndrome
MC Matesan, DJ Cross, DH Lewis… - Clinical Nuclear …, 2015 - journals.lww.com
Objectives Differential vulnerabilities of subregional dopamine neurons have been
suggested in movement disorders such as idiopathic Parkinson disease. In this study, we …
suggested in movement disorders such as idiopathic Parkinson disease. In this study, we …
[HTML][HTML] Two distinct degenerative types of nigrostriatal dopaminergic neuron in the early stage of parkinsonian disorders
T Kawazoe, K Sugaya, Y Nakata, M Okitsu… - Clinical Parkinsonism & …, 2024 - Elsevier
Introduction The present study characterized the degeneration of nigrostriatal dopaminergic
neurons in the early stages of parkinsonian disorders using integrative neuroimaging …
neurons in the early stages of parkinsonian disorders using integrative neuroimaging …
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