BACKGROUND AND PURPOSE: Brain tumor location has proved to be a prognostic factor
that may be associated with features of neoplastic origin. Mutation of p53 is an atypical …

Accumulating evidence has suggested that tumor location is linked to the genetic profile of
gliomas. Therefore, the aim of this study was to investigate the anatomical characteristics of …

Glioblastoma multiforme (GBM) is a heterogeneous group of tumors, and neuroimaging
characteristics have not been well‐defined in molecular subgroups. Eighty‐five patients with …

Background This study aims to evaluate the impact of tumor location on key molecular
alterations on a single voxel level in patients with newly diagnosed glioma. Methods A …

BACKGROUND AND PURPOSE: Tumor location has been shown to be a significant
prognostic factor in patients with glioblastoma. The purpose of this study was to characterize …

Background P53 mutation status is a pivotal biomarker for gliomas. Here, we developed a
machine-learning model to predict p53 status in lower-grade gliomas based on radiomic …

Background. Alteration of the tumor suppressor gene p53 is considered to be a critical step
in the development of human cancer. Changes in this gene have been detected in a wide …

Introduction MR imaging can noninvasively visualize tumor phenotype characteristics at the
macroscopic level. Here, we investigated whether somatic mutations are associated with …

Mutations in the p53 gene have been recognized in brain tumors, and clonal expansion of
p53 mutant cells has been shown to be associated with glioma progression. However …

OBJECTIVE: Immunostaining for p53 commonly is considered a marker of neoplasia.
Previous studies of nonneoplastic processes have yielded conflicting results. METHODS: To …