BACKGROUND AND PURPOSE: Impairment of macrophage polarization from a
proinflammatory macrophage type 1 (M1) population to an anti-inflammatory macrophage …

BACKGROUND AND PURPOSE: The purpose of this study was to probe the cellular
mechanism of healing in aneurysms after platinum coil embolization, by using multiple …

Introduction Macrophages and neutrophils have been separately implicated in cerebral
aneurysm formation. The interactions between different myeloid subsets and the …

Background and purpose Despite significant technical advances, recanalization rates after
endovascular therapy of ruptured intracranial aneurysms (IAs) remain a clinical challenge. A …

Background We have previously shown that monocyte chemotactic protein-1 (MCP-1)
promotes aneurysm healing. Objective To determine the temporal cascade and durability of …

Purpose Intracranial aneurysm (IA) rupture results in one of the most severe forms of stroke,
with severe neurological sequelae. Inflammation appears to drive aneurysm formation and …

Background Healing of intracranial aneurysms following endovascular treatment relies on
the organization of early thrombus into mature scar tissue and neointima formation …

Background and purpose Recanalization of post-embolization cerebral aneurysms remains
a serious problem that influences treatment outcomes. Matrix2 is a bioactive, bio …

Background The extent, rate, and source of endothelialization following coil embolization of
saccular aneurysms remains poorly understood. We performed a whole tissue mount, dual …

BACKGROUND AND PURPOSE: The purpose of this study was to clarify the cellular
mechanisms of aneurysmal healing by comparing histologic and immunohistochemical …