Brain temperature is increased during the first days of life in asphyxiated newborns: developing brain injury despite hypothermia treatment

ZP Owji, G Gilbert, C Saint-Martin… - American Journal of …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Therapeutic hypothermia is the current treatment for
neonates with hypoxic-ischemic encephalopathy. It is believed to work by decreasing the …

Brain perfusion in encephalopathic newborns after therapeutic hypothermia

AN Massaro, M Bouyssi-Kobar… - American Journal …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Cerebral perfusion patterns in neonates with HIE after
therapeutic hypothermia have not been well described. The objectives of this study were to …

Cerebral oxygen metabolism during and after therapeutic hypothermia in neonatal hypoxic–ischemic encephalopathy: a feasibility study using magnetic resonance …

AN Shetty, AM Lucke, P Liu, M Sanz Cortes… - Pediatric …, 2019 - Springer
Background Therapeutic hypothermia is the standard-of-care treatment for infants
diagnosed with moderate-to-severe hypoxic–ischemic encephalopathy (HIE). MRI for …

An in vivo assessment of regional brain temperature during whole-body cooling for neonatal encephalopathy

TW Wu, JL Wisnowski, RF Geisler, A Reitman… - The Journal of …, 2020 - Elsevier
Objective To assess differences in regional brain temperatures during whole-body
hypothermia and test the hypothesis that brain temperature profile is nonhomogenous in …

Prognostic utility of magnetic resonance imaging in neonatal hypoxic-ischemic encephalopathy: substudy of a randomized trial

JLY Cheong, L Coleman, RW Hunt… - … of pediatrics & …, 2012 - jamanetwork.com
Objective To investigate the effects of hypothermia treatment on magnetic resonance
imaging (MRI) patterns of brain injury in newborns with hypoxic-ischemic encephalopathy …

Brain temperature in neonates with hypoxic-ischemic encephalopathy during therapeutic hypothermia

TW Wu, C McLean, P Friedlich, J Wisnowski… - The Journal of …, 2014 - Elsevier
Objective To noninvasively determine brain temperature of neonates with hypoxic-ischemic
encephalopathy (HIE) during and after therapeutic hypothermia. Study design Using a …

Newborns referred for therapeutic hypothermia: association between initial degree of encephalopathy and severity of brain injury (what about the newborns with mild …

M Gagne-Loranger, M Sheppard, N Ali… - American journal of …, 2016 - thieme-connect.com
Objective The aim of this article was to describe the severity of brain injury and/or mortality in
a cohort of newborns referred for therapeutic hypothermia, in relation to the degree of …

Mild hypothermia and the distribution of cerebral lesions in neonates with hypoxic-ischemic encephalopathy

MA Rutherford, D Azzopardi, A Whitelaw, F Cowan… - …, 2005 - publications.aap.org
Hypothermia induced by whole-body cooling (WBC) and selective head cooling (SHC) both
reduce brain injury after hypoxia-ischemia in newborn animals, but it is not known how these …

Current practice of therapeutic hypothermia for mild hypoxic ischemic encephalopathy

CL Saw, A Rakshasbhuvankar, S Rao… - Journal of child …, 2019 - journals.sagepub.com
Context: Therapeutic hypothermia is the recommended treatment for neonates with
moderate or severe hypoxic ischemic encephalopathy (HIE). There is an increasing trend to …

Pilot study of treatment with whole body hypothermia for neonatal encephalopathy

D Azzopardi, NJ Robertson, FM Cowan… - …, 2000 - publications.aap.org
Background. There is extensive experimental evidence to support the investigation of
treatment with mild hypothermia after birth asphyxia. However, clinical studies have been …