Dynamic contrast agent–enhanced perfusion magnetic resonance (MR) imaging provides
physiologic information that complements the anatomic information available with …

Glioblastomas (GBMs), the most common primary brain tumor in adults, are characterized by
resistance to chemotherapy and radiotherapy. One of the defining characteristics of GBM is …

Glioblastoma multiforme (GBM) is characterized by exuberant angiogenesis, a key event in
tumor growth and progression. The pathologic mechanisms driving this change and the …

In contrast with the prevailing view that most tumors and metastases begin as avascular
masses, evidence is presented here that a subset of tumors instead initially grows by coopting …

… 3 d), but expression was not detected in nonmalignant stromal cells under the assay … (d)
in renal clear cell carcinoma cell lines, the loss of von Hippel-Lindau tumor suppressor function …

… D, Clustering of tumour samples by hierarchical clustering using all genes exhibiting variation
across the data set. E, Signal-to-noise rankings of genes comparing each tumour type to …

Ependymal tumors across age groups are currently classified and graded solely by histopathology.
It is, however, commonly accepted that this classification scheme has limited clinical …

… Blood vessels in wild-type and mutant ganglionic eminences by CD31 (a–d) and laminin
immunodetection (e–h). Arrows in a, c, e, g indicate normal blood vessels, arrowheads in b, d, f, …

BACKGROUND AND PURPOSE: Sensitivity, positive predictive value (PPV), and negative
predictive value (NPV) of conventional MR imaging in predicting glioma grade are not high. …

… (D and E) Growth-inhibition assays of Rat1A cells transduced with the indicated lentivirus (D)
… Cells were treated for 3 days (D) or for the indicated time (E). Cell viability was determined …