Clinical applications of metabolomics in oncology: a review
JL Spratlin, NJ Serkova, SG Eckhardt - Clinical cancer research, 2009 - AACR
Metabolomics, an omic science in systems biology, is the global quantitative assessment of
endogenous metabolites within a biological system. Either individually or grouped as a …
endogenous metabolites within a biological system. Either individually or grouped as a …
Intracranial mass lesions: dynamic contrast-enhanced susceptibility-weighted echo-planar perfusion MR imaging
S Cha, EA Knopp, G Johnson, SG Wetzel, AW Litt… - Radiology, 2002 - pubs.rsna.org
Dynamic contrast agent–enhanced perfusion magnetic resonance (MR) imaging provides
physiologic information that complements the anatomic information available with …
physiologic information that complements the anatomic information available with …
Glioma grading: sensitivity, specificity, and predictive values of perfusion MR imaging and proton MR spectroscopic imaging compared with conventional MR imaging
BACKGROUND AND PURPOSE: Sensitivity, positive predictive value (PPV), and negative
predictive value (NPV) of conventional MR imaging in predicting glioma grade are not high …
predictive value (NPV) of conventional MR imaging in predicting glioma grade are not high …
High-grade gliomas and solitary metastases: differentiation by using perfusion and proton spectroscopic MR imaging
M Law, S Cha, EA Knopp, G Johnson, J Arnett, AW Litt - Radiology, 2002 - pubs.rsna.org
PURPOSE: To determine whether perfusion-weighted and proton spectroscopic MR
imaging can be used to differentiate high-grade primary gliomas and solitary metastases on …
imaging can be used to differentiate high-grade primary gliomas and solitary metastases on …
Amide proton transfer imaging of adult diffuse gliomas: correlation with histopathological grades
O Togao, T Yoshiura, J Keupp, A Hiwatashi… - Neuro …, 2014 - academic.oup.com
Background Amide proton transfer (APT) imaging is a novel molecular MRI technique to
detect endogenous mobile proteins and peptides through chemical exchange saturation …
detect endogenous mobile proteins and peptides through chemical exchange saturation …
Magnetic resonance spectroscopy of the brain: review of metabolites and clinical applications
Magnetic resonance imaging (MRI) provides anatomic images and morphometric
characterization of disease, whereas magnetic resonance spectroscopy (MRS) provides …
characterization of disease, whereas magnetic resonance spectroscopy (MRS) provides …
Differentiation of recurrent glioblastoma multiforme from radiation necrosis after external beam radiation therapy with dynamic susceptibility-weighted contrast …
Purpose To investigate whether cerebral blood volume (CBV), peak height (PH), and
percentage of signal intensity recovery (PSR) measurements derived from the results of T2 …
percentage of signal intensity recovery (PSR) measurements derived from the results of T2 …
Imaging of brain tumors: MR spectroscopy and metabolic imaging
A Horská, PB Barker - Neuroimaging Clinics, 2010 - neuroimaging.theclinics.com
Localized proton magnetic resonance spectroscopy (MRS) of the human brain, first reported
more than 20 years ago, 1–3 is a mature methodology that is used clinically in many medical …
more than 20 years ago, 1–3 is a mature methodology that is used clinically in many medical …
Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy
Mutations of the isocitrate dehydrogenase 1 and 2 genes (IDH1 and IDH2) are commonly
found in primary brain cancers. We previously reported that a novel enzymatic activity of …
found in primary brain cancers. We previously reported that a novel enzymatic activity of …
Relative cerebral blood volume values to differentiate high-grade glioma recurrence from posttreatment radiation effect: direct correlation between image-guided …
LS Hu, LC Baxter, KA Smith… - American Journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Differentiating tumor growth from posttreatment radiation
effect (PTRE) remains a common problem in neuro-oncology practice. To our knowledge …
effect (PTRE) remains a common problem in neuro-oncology practice. To our knowledge …