PURPOSE To investigate the cost-effectiveness of high-dose MR contrast studies in the
management of brain metastases. METHODS During the phase III clinical trial of high-dose …

Brain metastases occur in about 25% of patients (1) with cancer and are often diagnosed
within the first year after the diagnosis of the primary tumor (2). The treatment of patients with …

PURPOSE Although studies obtained with triple-dose contrast administration can show
more brain metastases than those obtained with single-dose contrast material in patients …

PURPOSE To evaluate the effect of MR contrast dose versus delayed imaging time on the
detection of metastatic brain lesions based on lesion size. METHODS Contrast MR …

OBJECT Contrast-enhanced MRI is the preeminent diagnostic test for brain metastasis (BM).
Detection of BMs for stereotactic radiosurgery (SRS) planning may improve with a time delay …

Purpose To evaluate the diagnostic performance of a double-dose administration of
gadolinium for brain metastases at 3 T in a systematic observer test. Materials and Methods …

PURPOSE To assess the effectiveness and safety of higher doses of gadoteridol in the MR
evaluation of patients with brain metastases. MATERIALS AND METHODS Thirty-one …

Contrast-enhanced MR studies were compared with noncontrast MR and contrast-enhanced
CT scans in the evaluation of intraparenchymal brain metastases. Fifty consecutive …

Purpose To compare the diagnostic efficacy of a standard and cumulative triple dose of
magnetic resonance (MR) imaging contrast agent in the evaluation of brain metastases …

Sze et al in this issue of American Journal of Neuroradiology (see page 821) renew the
controversy surrounding the best way to screen for brain metastases. This remains very …