Abstract
SUMMARY: We observed a lesion pattern in a series of 4 cases of RANBP2-mutation–linked acute necrotizing encephalopathy, which appears to be specific for this condition. The setting of synchronous bilateral mammillary, amygdaloid, and lateral geniculate lesions, along with claustro-parahippocampal lesions, can serve as a diagnostic tool in this condition. We add several further details to the MR imaging features of the typical brain lesions encountered in this disease.
ABBREVIATIONS:
- ANE1
- acute necrotizing encephalopathy type 1
- RANBP2
- RAN binding protein 2
- © 2021 by American Journal of Neuroradiology