Abstract
SUMMARY: The Kety-Schmidt technique provides quantitative measurement of whole-brain CBF. CBF is measured as the area between the arterial and venous washout curves of a diffusible tracer. Oxygen extraction and metabolism may be calculated from arterial and venous samples. In this report, we present a method for performing these measurements in an MR imaging environment. This technique could be useful for validation of MR imaging methods of hemodynamic and metabolic measurements in humans.
Abbreviations
- CMRO2
- cerebral metabolic rate for oxygen consumption
- IM
- intramuscularly
- NDIR
- nondispersive infrared
- OEF
- oxygen extraction fraction
- © 2014 American Society of Neuroradiology
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