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Research ArticleBRAIN

Persistence of Gadolinium in CSF: A Diagnostic Pitfall in Patients with End-stage Renal Disease

Ansaar T. Rai and Jeffery P. Hogg
American Journal of Neuroradiology August 2001, 22 (7) 1357-1361;
Ansaar T. Rai
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Jeffery P. Hogg
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    fig 1.

    Sagittal (A) 500/8/1 (TR/TE/excitation) and axial (B) 566/12/1 precontrast T1-weighted and axial FLAIR (C) 10002/97.5/1 images of the brain demonstrate normal signal intensity of the CSF with normal contrast enhancement between the CSF and adjacent brain.

    Sagittal (D) 500/8/1 and axial (E) 566/12/1 precontrast T1-weighted images 10 days later, demonstrate increased signal intensity within the subarachnoid space, manifested by an isointense appearance of the sulci as compared with the adjacent brain. Additionally, there is increased signal intensity within the ocular globes on the axial image. The axial FLAIR (F) 10002/97.5/1 image demonstrates diffuse significant increased signal intensity within the subarachnoid space and the ventricles. A–F were filmed at the same values for window and level, and were performed on the same scanner.

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    fig 2.

    Sagittal (A) 516/12/2 and axial (B) 686/11.6/2 precontrast T1-weighted images of the spine demonstrate diffuse increased signal intensity within the subarachnoid space. Sagittal precontrast T1-weighted (C) 550/12/2 image of the lumbar spine performed 2 weeks later shows resolution of the previously seen increased signal intensity and a normal signal within the CSF. A–C were filmed at the same values for window and level, and were performed on the same scanner

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American Journal of Neuroradiology: 22 (7)
American Journal of Neuroradiology
Vol. 22, Issue 7
1 Aug 2001
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Persistence of Gadolinium in CSF: A Diagnostic Pitfall in Patients with End-stage Renal Disease
Ansaar T. Rai, Jeffery P. Hogg
American Journal of Neuroradiology Aug 2001, 22 (7) 1357-1361;

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Persistence of Gadolinium in CSF: A Diagnostic Pitfall in Patients with End-stage Renal Disease
Ansaar T. Rai, Jeffery P. Hogg
American Journal of Neuroradiology Aug 2001, 22 (7) 1357-1361;
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Cited By...

  • Differential diagnosis of hyperintense cerebrospinal fluid on fluid-attenuated inversion recovery images of the brain. Part I: pathological conditions
  • Persistence of Gadolinium Contrast Enhancement in CSF: A Possible Harbinger of Gadolinium Neurotoxicity?
  • Gadolinium encephalopathy in a patient with renal failure
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