Research ArticleBRAIN
Tissue at Risk Is Overestimated in Perfusion-Weighted Imaging: MR Imaging in Acute Stroke Patients without Vessel Recanalization
Thomas Kucinski, Dirk Naumann, René Knab, Volker Schoder, Susanne Wegener, Jens Fiehler, Amitava Majumder, Joachim Röther and Hermann Zeumer
American Journal of Neuroradiology April 2005, 26 (4) 815-819;
Thomas Kucinski
Dirk Naumann
René Knab
Volker Schoder
Susanne Wegener
Jens Fiehler
Amitava Majumder
Joachim Röther
References
- ↵Moseley ME, Cohen Y, Mintorovitch J, et al. Early detection of regional cerebral ischemia in cats: comparison of diffusion- and T2-weighted MRI and spectroscopy. Magn Reson Med 1990;14:330–346
- Fisher M, Prichard JW, Warach S. New magnetic resonance techniques for acute ischemic stroke. JAMA 1995;274:908–911
- ↵Schellinger PD, Jansen O, Fiebach JB, et al. Feasibility and practicality of MR imaging of stroke in the management of hyperacute cerebral ischemia. AJNR Am J Neuroradiol 2000;21:1184–1189
- ↵Schlaug G, Benfield A, Baird AE, et al. The ischemic penumbra: operationally defined by diffusion and perfusion MRI. Neurology 1999;53:1528–1537
- ↵Neumann Haefelin T, Wittsack HJ, Wenserski F, et al. Diffusion- and perfusion-weighted MRI: the DWI/PWI mismatch region in acute stroke. Stroke 1999;30:1591–1597
- ↵Sorensen AG, Copen WA, Ostergaard L, et al. Hyperacute stroke: simultaneous measurement of relative cerebral blood volume, relative cerebral blood flow, and mean tissue transit time. Radiology 1999;210:519–527
- ↵Albers GW. Expanding the window for thrombolytic therapy in acute stroke: the potential role of acute MRI for patient selection. Stroke 1999;30:2230–2237
- ↵Rother J, Schellinger PD, Gass A, et al. Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke <6 hours. Stroke 2002;33:2438–2445
- ↵Donnan GA, Davis SM. Neuroimaging, the ischaemic penumbra, and selection of patients for acute stroke therapy. Lancet Neurol 2002;1:417–425
- ↵
- ↵Ostergaard L, Sorensen AG, Kwong KK, et al. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II. Experimental comparison and preliminary results. Magn Reson Med 1996;36:726–736
- ↵Schellinger PD, Fiebach JB, Hacke W. Imaging-based decision making in thrombolytic therapy for ischemic stroke: present status. Stroke 2003;34:575–583
- ↵Fiehler J, Foth M, Kucinski T, et al. Severe ADC decreases do not predict irreversible tissue damage in humans. Stroke 2002;33:79–86
- ↵Kucinski T, Vaterlein O, Glauche V, et al. Correlation of apparent diffusion coefficient and computed tomography density in acute ischemic stroke. Stroke 2002;33:1786–1791
- ↵Astrup J, Siesjo BK, Symon L. Thresholds in cerebral ischemia: the ischemic penumbra. Stroke 1981;12:723–725
- ↵Kucinski T, Koch C, Eckert B, et al. Collateral circulation is an independent radiological predictor of outcome after thrombolysis in acute ischaemic stroke. Neuroradiology 2003;45:11–18
- ↵
- ↵Singer OC, De Rochemont Rdu M, Foerch C, et al. Relation between relative cerebral blood flow, relative cerebral blood volume, and mean transit time in patients with acute ischemic stroke determined by perfusion-weighted MRI. J Cereb Blood Flow Metab 2003;23:605–611
- ↵Lin W, Lee JM, Lee YZ, et al. Temporal relationship between apparent diffusion coefficient and absolute measurements of cerebral blood flow in acute stroke patients. Stroke 2003;34:64–70
- ↵Schaefer PW, Ozsunar Y, He J, et al. Assessing tissue viability with MR diffusion and perfusion imaging. AJNR Am J Neuroradiol 2003;24:436–443
- ↵Butcher K, Parsons M, Baird T, et al. Perfusion thresholds in acute stroke thrombolysis. Stroke 2003;34:2159–2164
- Liu Y, Karonen JO, Vanninen RL, et al. Cerebral hemodynamics in human acute ischemic stroke: a study with diffusion- and perfusion-weighted magnetic resonance imaging and SPECT. J Cereb Blood Flow Metab 2000;20:910–920
- Shih LC, Saver JL, Alger JR, et al. Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue. Stroke 2003;34:1425–1430
- ↵Rohl L, Ostergaard L, Simonsen CZ, et al. Viability thresholds of ischemic penumbra of hyperacute stroke defined by perfusion-weighted MRI and apparent diffusion coefficient. Stroke 2001;32:1140–1146
- ↵
- ↵
- ↵Schellinger PD, Fiebach JB, Jansen O, et al. Stroke magnetic resonance imaging within 6 hours after onset of hyperacute cerebral ischemia. Ann Neurol 2001;49:460–469
- ↵Rordorf G, Koroshetz WJ, Copen WA, et al. Regional ischemia and ischemic injury in patients with acute middle cerebral artery stroke as defined by early diffusion-weighted and perfusion-weighted MRI. Stroke 1998;29:939–943
- ↵Fiehler J, Knudsen K, Kucinski T, et al. Predictors of apparent diffusion coefficient normalization in stroke patients. Stroke 2004;35:514–519
- ↵Arnold M, Nedeltchev K, Mattle HP, et al. Intra-arterial thrombolysis in 24 consecutive patients with internal carotid artery T occlusions. J Neurol Neurosurg Psychiatry 2003;74:739–742
- ↵Kucinski T, Koch C, Grzyska U, et al. The predictive value of early CT and angiography for fatal hemispheric swelling in acute stroke. AJNR Am J Neuroradiol 1998;19:839–846
In this issue
Advertisement
Tissue at Risk Is Overestimated in Perfusion-Weighted Imaging: MR Imaging in Acute Stroke Patients without Vessel Recanalization
Thomas Kucinski, Dirk Naumann, René Knab, Volker Schoder, Susanne Wegener, Jens Fiehler, Amitava Majumder, Joachim Röther, Hermann Zeumer
American Journal of Neuroradiology Apr 2005, 26 (4) 815-819;
Tissue at Risk Is Overestimated in Perfusion-Weighted Imaging: MR Imaging in Acute Stroke Patients without Vessel Recanalization
Thomas Kucinski, Dirk Naumann, René Knab, Volker Schoder, Susanne Wegener, Jens Fiehler, Amitava Majumder, Joachim Röther, Hermann Zeumer
American Journal of Neuroradiology Apr 2005, 26 (4) 815-819;
Jump to section
Related Articles
Cited By...
- Infarct Volume Is a Pivotal Biomarker After Intra-Arterial Stroke Therapy
- CT Perfusion Mean Transit Time Maps Optimally Distinguish Benign Oligemia from True "At-Risk" Ischemic Penumbra, but Thresholds Vary by Postprocessing Technique
- Recommendations for Imaging of Acute Ischemic Stroke: A Scientific Statement From the American Heart Association
- Comparison of 10 Perfusion MRI Parameters in 97 Sub-6-Hour Stroke Patients Using Voxel-Based Receiver Operating Characteristics Analysis
- Blood Oxygen Level-Dependent MRI Allows Metabolic Description of Tissue at Risk in Acute Stroke Patients
- Identification of Penumbra and Infarct in Acute Ischemic Stroke Using Computed Tomography Perfusion-Derived Blood Flow and Blood Volume Measurements
This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.
More in this TOC Section
Similar Articles
Advertisement