Abstract
SUMMARY: Primary AT/RT is a rare highly malignant tumor of the CNS, usually occurring in children younger than 5 years of age. The objective of this study was to characterize the CT and MR imaging findings in a series of 5 adult patients with pathologically proved AT/RT. All 5 AT/RTs were supratentorial. In 2 patients who underwent nonenhanced CT, the tumors appeared isoattenuated, and 1 of the 2 tumors contained calcifications. Solid portions of the tumors on MR imaging were isointense on T1-weighted, T2-weighted, and FLAIR images, and 1 case showed restricted diffusion on DWI. The tumors also demonstrated a bandlike rim of strong enhancement surrounding a central cystic area on contrast-enhanced T1-weighted imaging. One tumor was associated with destruction of the calvaria. Although AT/RTs can have nonspecific findings, the tumors in our series were large and isointense on T1-weighted, T2-weighted, and FLAIR images with central necrosis and prominent rim enhancement.
Abbreviations
- ADC
- apparent diffusion coefficient
- AT/RT
- atypical teratoid/rhabdoid tumor
- CNS
- central nervous system
- DWI
- diffusion-weighted imaging
- FLAIR
- fluid-attenuated inversion recovery
- L
- left
- mRNA
- messenger ribonucleic acid
- N/A
- not available
- ND
- not depicted
- OS
- overall survival
- PNET
- primitive neuroectodermal tumor
- PR
- partial resection
- R
- right
- TR
- total resection
- Copyright © American Society of Neuroradiology