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Tumor stiffness properties were prospectively quantified in 18 patients with histologically proved gliomas using MR elastography. Images were acquired on a 3T MR imaging unit with a vibration frequency of 60 Hz. Tumor stiffness was compared with unaffected contralateral white matter, across tumor grade, and by IDH1-mutation status. Gliomas were softer than healthy brain parenchyma, 2.2kPa compared with 3.3kPa, with grade IV tumors softer than grade II. MR elastography demonstrated that not only were gliomas softer than normal brain but the degree of softening was directly correlated with tumor grade and IDH1-mutation status.