More articles from Adult Brain
- The Added Value of Volume-of-Interest C-Arm CT Imaging during Endovascular Treatment of Intracranial Aneurysms
VOI C-arm CT images were obtained in 28 patients undergoing endovascular treatment of intracranial aneurysms and the VOI images were reconstructed by using a novel prototype reconstruction algorithm to minimize truncation artifacts from double collimation. The reconstruction accuracy of VOI C-arm CT images was assessed quantitatively by comparing them with the full-head noncollimated images. Quality of VOI C-arm CT images was comparable with that of the standard Feldkamp, Davis, and Kress reconstruction of noncollimated C-arm CT images. The authors conclude that VOI imaging allows multiple 3D C-arm CT acquisitions and provides information related to device expansion, parent wall apposition, and neck coverage during the procedure, with very low additional radiation exposure to the patient.
- Computational Identification of Tumor Anatomic Location Associated with Survival in 2 Large Cohorts of Human Primary Glioblastomas
Preoperative T1 anatomic MR images of 384 patients with glioblastomas were evaluated by an automated computational image-analysis pipeline to determine the anatomic locations of tumor in each patient. Voxel-based differences in tumor location between good and poor survival groups identified in the training cohort were used to classify patients in The Cancer Genome Atlas cohort into 2 brain-location groups, for which clinical features, messenger RNA expression, and copy number changes were compared. Tumors in the right occipitotemporal periventricular white matter were significantly associated with poor survival in both training and test cohorts. Tumors in the right periatrial location were associated with hypoxia pathway enrichment and PDGFRA amplification. The authors conclude that voxel-based location in glioblastoma is associated with patient outcome and may have a potential role for guiding personalized treatment.
- Revised Recommendations of the Consortium of MS Centers Task Force for a Standardized MRI Protocol and Clinical Guidelines for the Diagnosis and Follow-Up of Multiple Sclerosis
This is a comprehensive group of guidelines for imaging patients with demyelinating disease, from an international group of neurologists and radiologists. Suggestions for MR imaging protocols are given for the brain, for surveillance imaging for progressive multifocal leukoencephalopathy, for spinal cord imaging, and for the orbit. Recommendations are also given for what type of material should be included in the report.