More articles from Neurodegenerative Disorder Imaging
- Clinical Improvement after Shunt Surgery in Patients with Idiopathic Normal Pressure Hydrocephalus Can Be Quantified by Diffusion Tensor Imaging
This study investigated DTI parameter alterations in pre- and postshunt implantation in patients with iNPH and the relationship between DTI parameters and clinical improvement. Cognitive domain improvement after surgery correlated with preoperative DTI values of cingulate gyrus, uncinate fasciculus, superior longitudinal fasciculus, or corpus callosum, which are regions involved in memory and psychomotor speed processes.
- Alzheimer Disease Anti-Amyloid Immunotherapies: Imaging Recommendations and Practice Considerations for Monitoring of Amyloid-Related Imaging Abnormalities
This review discusses the 3 key MRI sequences for ARIA monitoring and standardized imaging protocols and provides imaging recommendations for 3 key patient scenarios. All patients on anti-amyloid immunotherapy should have T2* gradient-recalled echo (to evaluate for ARIA-H), 2D or 3D T2 FLAIR (to evaluate for ARIA-E), and DWI (to differentiate ARIA-E from acute ischemia). Patient imaging scenarios are 1) baseline dementia diagnosis/treatment enrollment evaluation, 2) asymptomatic ARIA monitoring, and 3) evaluation of the symptomatic patient on anti-amyloid immunotherapy.